TY - JOUR
T1 - Evaluation of the antifungal activity of marine actinomycetes isolates against the phytopathogenic fungi Colletotrichum siamense KA
T2 - A preliminary study for new antifungal compound discovery
AU - Fadhilah, Qonita Gina
AU - Santoso, Iman
AU - Maryanto, Andi Eko
AU - Abdullah, Sarini
AU - Yasman, Yasman
N1 - Funding Information:
This research was supported by Grant International Indexed Publication (PUTI) Sains, Technology, and Health 2020 from Universitas Indonesia to Dr. rer. nat. Yasman, M.Sc. (No. NKB-4903/UN2.RST/ HKP.05.00/2020). We are grateful to Mazytha Kinanti
Funding Information:
This research was supported by Grant International Indexed Publication (PUTI) Sains, Technology, and Health 2020 from Universitas Indonesia to Dr. rer. nat. Yasman, M.Sc. (No. NKB-4903/UN2.RST/HKP.05.00/2020). We are grateful to Mazytha Kinanti
Publisher Copyright:
© 2021. Fadhilah QG et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2021
Y1 - 2021
N2 - Marine actinomycetes are being explored to discover potential actinomycetes that produce antifungal compounds. In a previous study, marine actinomycetes isolates from the mangrove ecosystem were found to inhibit growth of the phytopathogenic fungi Colletotrichum siamense KA. In this study, the three of these isolates with the highest antagonistic activity—SM11, SM14, and SM15—were evaluated for their antifungal activity using antibiosis assay. The fermentation was performed in SCB:PDB medium (1:1) for 6, 9, and 12 days. The results showed that SM14 was the strongest potential isolate; it inhibited the growth of C. siamense KA on average up to 64.90% for 12 days on PDA filtrate medium. Molecular identification showed SM14 was closely related to Streptomyces sanyensis, but had differences in morphological and biochemical characteristics compared to SM11 or SM15. This indicated that the three isolates were different strains and may challenge further research on identifying and analyzing their antifungal compounds.
AB - Marine actinomycetes are being explored to discover potential actinomycetes that produce antifungal compounds. In a previous study, marine actinomycetes isolates from the mangrove ecosystem were found to inhibit growth of the phytopathogenic fungi Colletotrichum siamense KA. In this study, the three of these isolates with the highest antagonistic activity—SM11, SM14, and SM15—were evaluated for their antifungal activity using antibiosis assay. The fermentation was performed in SCB:PDB medium (1:1) for 6, 9, and 12 days. The results showed that SM14 was the strongest potential isolate; it inhibited the growth of C. siamense KA on average up to 64.90% for 12 days on PDA filtrate medium. Molecular identification showed SM14 was closely related to Streptomyces sanyensis, but had differences in morphological and biochemical characteristics compared to SM11 or SM15. This indicated that the three isolates were different strains and may challenge further research on identifying and analyzing their antifungal compounds.
KW - antibiosis assay
KW - antifungal activity
KW - marine actinomycetes
KW - Streptomyces sanyensis
UR - http://www.scopus.com/inward/record.url?scp=85120965161&partnerID=8YFLogxK
U2 - 10.3897/PHARMACIA.68.E72817
DO - 10.3897/PHARMACIA.68.E72817
M3 - Article
AN - SCOPUS:85120965161
SN - 0428-0296
VL - 68
SP - 837
EP - 843
JO - Pharmacia
JF - Pharmacia
IS - 4
ER -
