Evaluation of myometrial invasion and cervical involvement in type I endometrial cancer using diffusion-weighted magnetic resonance imaging

Hariyono Winarto, Brian Prima Artha, Sahat B. Matondang, Tantri Hellyanti, Aria Kekalih

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Surgical procedure and adjuvant treatment of type I endometrial cancer were affected by some variables assessed preoperatively. Diffusion-weighted magnetic resonance imaging (DWI) is a promising modality in evaluating myometrial invasion and cervical involvement, investigating the diagnostic values of DWI in assessing myometrial invasion and cervical involvement. Methods: A cross-sectional study was conducted. This study involved all type I endometrial cancer patients in Dr. Cipto Mangunkusumo Hospital from April 2016 until April 2019. The depth of myometrial invasion and cervical involvement was examined using 1.5-T MR unit. The result was compared to the surgical pathologic findings as the reference standard. Results: 34 types I endometrial cancer patients were enrolled in this study. The sensitivity of DWI in evaluating myometrial invasion and cervical involvement in type I endometrial cancer was 94.12% and 57.14%, while the specificity was 64.71% and 92.59%, respectively. Conclusion: DWI can provide reliable prognostic variable information about the myometrial invasion and cervical involvement in the preoperative preparation of endometrial cancer patients.

Original languageEnglish
Pages (from-to)4-6
Number of pages3
JournalInternational Journal of Applied Pharmaceutics
Volume12
Issue numberSpecial Issue 3
DOIs
Publication statusPublished - 2020

Keywords

  • Cervical involvement
  • Diffusion-weighted magnetic resonance imaging
  • Endometrial cancer
  • Myometrial invasion

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