Evaluating the efficacy of lotion containing black rice bran (Oryza sativa L. indica) extract as skin brightening agent: A clinical trial

Mahdi Jufri, Afifah Vardhani, Erni Purwaningsih

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background: Ultraviolet exposure is an extrinsic factor to initiate melanogenesis, the process of melanin formation in the skin. Nowadays, natural ingredients tend to be more prevalent in cosmetic formulations due to consumers’ concern about synthetic ingredients and the risks they may represent for human health. Rice bran, the outer layer of a rice grain, can be utilized as a skin-lightening agent. Objectives: This study aimed to determine the efficacy of a lotion containing black rice bran (Oryza sativa L. indica) ethanolic extract as a skin lightening agent. Methods: The black rice bran ethanolic extract was formulated into oil in water (o/w) lotion. In this study, 34 women applied the lotion at one side of the forearm and base placebo lotion as control at the other side of forearm. The results were tested with a paired t-test by GraphPad Prism 8.3.0 software. Results: There was a significant decrease in the melanin index and erythema index in the forearm with a lotion containing black rice bran extract (P-value < 0.0001). Conclusions: The lotion containing 10% black rice bran extract was effective as a skin lightener because it effectively reduced skin melanin production when applied topically.

Original languageEnglish
Article numbere114152
JournalJundishapur Journal of Natural Pharmaceutical Products
Volume16
Issue number4
DOIs
Publication statusPublished - 2021

Keywords

  • Black Rice Bran
  • Clinical Trials
  • Natural Product
  • Oryza sativa L. indica
  • Skin Lightening Agent

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