Maxillofacial screw used to overcome facial trauma problem in the Craniomaxillofacial region often affects the aesthetic, function, and structure of the patient's face. The main objective of this study was to evaluate the influence of manufacturing variable to the mini screw performance based on pull out testing and driving torque testing. The method was based on ASTM F-543 to quantify pull out strength and driving torque forces. Prior to the experimental testing, all the specimens were manufactured using CNC machine citizen A-20 with several different manufacturing parameters. The result of pull out testing the specimens of mini screw 130, mini screw 131, mini screw 132 have insignificant different with the commercial product because the Pvalue = 0,287. Otherwise mini screw 133, mini screw 134, mini screw 135, mini screw 136, and mini screw 108 have significant different with the value bellow the commercial product with the Pvalue = 0,000. For the driving torque testing, specimens 131, 132, 133, 134, 135, 136, and 108 have insignificant different to each other with the Pvalue = 0,414. If all the specimens compared to the commercial product the Pvalue become 0,002 it means the difference between the mini specimens and commercial product are significant.