Solution tumescente d’épinéphrine à un pour un million en chirurgie de la main: analyse des études expérimentales et cliniques

Translated title of the contribution: Epinephrine one-per-mil tumescent solution in hand surgery: Review of experimental and clinical studies

Research output: Contribution to journalShort surveypeer-review

Abstract

One-per-mil epinephrine solution (1:1,000,000) injected as a tumescent has been used in several hand and upper-limb surgery cases as a substitute for tourniquet. However, reviews of its effectiveness are still lacking. A comprehensive review was conducted based on PubMed, Scopus, Science Direct, Cochrane Library, and Semantic Scholar database search of relevant studies using the keyword “one-per-mil.” Studies not using the exact one-per-mil tumescent solution formula were excluded. The review of clinical studies was conducted according to PRISMA guidelines. Epinephrine and the hydrostatic vasocompressive effect created bloodless operative fields, with 100% experimental flap survival after ischemic insult. The technique was effective in creating bloodless operative fields in 36.3% of varied hand and upper-limb surgery cases and in fully awake surgery. Current studies show that one-per-mil tumescent solution is safe and effective, enabling use of tourniquet to be avoided.

Translated title of the contributionEpinephrine one-per-mil tumescent solution in hand surgery: Review of experimental and clinical studies
Original languageFrench
Pages (from-to)554-559
Number of pages6
JournalHand Surgery and Rehabilitation
Volume40
Issue number5
DOIs
Publication statusPublished - Oct 2021

Keywords

  • Epinephrine
  • Hand injury
  • Lidocaine
  • Local anesthesia
  • Wakefulness

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