Epinephrine in the tumescent technique for hypospadia surgery

Theddeus O.H. Prasetyono, Nandita M. Putri

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The use of tumescent technique, which contains epinephrine, in penile surgery has not been reported previously. Two patients with hypospadias had reconstructive operation using tumescent technique with a ”One-per-Mil” tumescent solution containing epinephrine intra-operatively. The results was a clear operation field, almost bloodless during dissection, and no complication on the penis after epinephrine injection with minimal edema. Apparently, the “One-per-Mil” tumescent solution acts as a natural hydro-dissector creating avascular anatomic tissue planes for easier and more rapid dissection in surgery for hypospadias. We suggest that epinephrine is safe to be injected in penis as a future area of clinical practice.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalMedical Journal of Indonesia
Issue number3
Publication statusPublished - Aug 2012


  • Epinephrine
  • Hypospadia
  • Tumescent technique


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