Emerging Resistance Pathogen: Recent Situation in Asia, Europe, USA, Middle East, and Indonesia

One of the health problems in Indonesia is caused by infectious diseases. The use of antibiotics in for infections should be included in the management of patients. Wide use of antibioticsfaces us to a new problem, since it will cause the increased number of resistance pathogens against antibiotics. Carbapenem is one of the most frequent group of antibiotics used in managing patients in intensive care units. Considering that there is possibility in the emerging resistancepathogens against carbapenem, a research was conducted to observe the resistance patternof some pathogens against meropenem and other antibiotics. The method used in this study wasthe disc diffusion method, according to NCCLS standard. The result showed that the sensitivity of Gram negative bacteria against meropenem was 96.9% (281/291), while the sensitivity of Grampositive bacteria against meropenem was 91% (131/144). A decreased sensitivity was found inmethicillin resistance Staphylococcus aureus (MRSA) against meropenem 72.7% (8/11). Many other antibiotics also showed a decreased sensitivity. This study showed that there were differences in antibiotic susceptibility patterns among different countries in the world.