Ekspresi HER2/neu(c-ErbB2) pada Kanker Kolorektal

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Abstract

Colorectal cancer is a neoplasia of colon and rectum ,and also the 3rd leading cause of morbidity and mortality among men and women in the world. HER2 expression has controversial results ranging from 0-83% and never been pubiished in lndonesia. This research aims to study HER2 expression in colorectal cancer. Cross-sectional study was conducted in 51 cases of colorectal cancer from January 2011 until December 2012 in Pathology Department of Cipto Mangunkusumo Hospital. Patient characteristic was reviewed from medical record and histopathologic was evaluated from HE slides. lmunohistochemistry staining used anti HER2 polyclonal antibody frorn DAKO. Mean age was 57.8113.54 years, 58.8% were males and 41.2o4 were females. Positive HER2 was 5 cases (9.8%).
Original languageIndonesian
JournalMajalah Kedokteran Andalas
Publication statusPublished - 2014

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