Efficacy of silver diamine fluoride and combination with CO₂ laser in reducing dentin hypersensitivity

Silver diamine fluoride application and CO2 laser exposure are new alternative treatments for dentin hypersensitivity. The purpose of this study was to evaluate the efficacy of silver diamine fluoride and CO2 laser in reducing the dentin hypersensitivity score. The study consisted of a single-blind, split-mouth design, and a randomized controlled trial involving 16 subjects with symptoms of sensitive teeth, with at least two hypersensitive teeth that were positive in evaporative or thermal tests. Silver diamine fluoride and CO2 laser were applied to the surfaces of the subjects' teeth. This clinical study demonstrated that the application of silver diamine fluoride and CO2 laser reduced dentin hypersensitivity significantly (p = 0.000 for evaporative and thermal stimuli).