Efficacy of lozenges containing kepel fruit (Stelechocarpus Burahol) extract for controlling oral malodor

Abrijanto Soen Bing, Abdul Mun’Im, Anton Rahardjo

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Objective: The aim of this study was to determine the effect of lozenges containing kepel fruit (Stelechocarpus burahol) in controlling oral malodor. Methods: This study used crossover randomized control trial design. Each of the 30 research subjects received all three treatments at different times: Kepel, xylitol, and placebo lozenges. The subjects used lozenges in the morning after breakfast and afternoon after lunch. Examinations of oral malodor were performed thrice: Immediately after waking up, after breakfast, and after lunch. Measured oral odor variables included organoleptic score and H2S, CH3SH, and (CH3)2S levels. Results: Effect of burahol fruit extract lozenges was comparable to that of xylitol gum in reducing the H2S, CH3SH, and (CH3)2S levels and organoleptic scores of the subjects. Conclusion: Lozenges containing burahol fruit extract were effective in controlling oral malodor (halitosis).

Original languageEnglish
Pages (from-to)185-189
Number of pages5
JournalInternational Journal of Applied Pharmaceutics
Issue numberSpecial Issue 1
Publication statusPublished - 1 Dec 2018


  • Halitosis
  • Kepel
  • Oral malodor
  • Stelechocarpus burahol
  • Volatile sulfur compound


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