Efficacy of javanese turmeric ethanol extract in eradicating streptococcus sanguinis and porphyromonas gingivalis biofilm

Rezon Yanuar; Dewi Fatma Suniarti; Widurini Djohan

doi:10.22159/ijap.2019.v11s1.155

Efficacy of javanese turmeric ethanol extract in eradicating streptococcus sanguinis and porphyromonas gingivalis biofilm

Rezon Yanuar, Dewi Fatma Suniarti, Widurini Djohan

Department of Oral Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identified Javanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms. Methods: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. The percentage of eradication was tested using the microtetrazolium assay. Results: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is more effective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation. Conclusion: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms.

Original language	English
Pages (from-to)	18-22
Number of pages	5
Journal	International Journal of Applied Pharmaceutics
Volume	11
DOIs	https://doi.org/10.22159/ijap.2019.v11s1.155
Publication status	Published - Apr 2019

Keywords

Biofilm eradication
Identified Javanese turmeric ethanol extract
Porphyromonas gingivalis
Streptococcus sanguinis

Access to Document

10.22159/ijap.2019.v11s1.155

Cite this

@article{59879bfd74e84546bb6ec0501f393266,

title = "Efficacy of javanese turmeric ethanol extract in eradicating streptococcus sanguinis and porphyromonas gingivalis biofilm",

abstract = "Objective: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identified Javanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms. Methods: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. The percentage of eradication was tested using the microtetrazolium assay. Results: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is more effective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation. Conclusion: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms.",

keywords = "Biofilm eradication, Identified Javanese turmeric ethanol extract, Porphyromonas gingivalis, Streptococcus sanguinis",

author = "Rezon Yanuar and Suniarti, {Dewi Fatma} and Widurini Djohan",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors.",

year = "2019",

month = apr,

doi = "10.22159/ijap.2019.v11s1.155",

language = "English",

volume = "11",

pages = "18--22",

journal = "International Journal of Applied Pharmaceutics",

issn = "0975-7058",

publisher = "Innovare Academics Sciences Pvt. Ltd",

}

TY - JOUR

T1 - Efficacy of javanese turmeric ethanol extract in eradicating streptococcus sanguinis and porphyromonas gingivalis biofilm

AU - Yanuar, Rezon

AU - Suniarti, Dewi Fatma

AU - Djohan, Widurini

PY - 2019/4

Y1 - 2019/4

N2 - Objective: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identified Javanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms. Methods: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. The percentage of eradication was tested using the microtetrazolium assay. Results: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is more effective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation. Conclusion: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms.

AB - Objective: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identified Javanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms. Methods: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. The percentage of eradication was tested using the microtetrazolium assay. Results: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is more effective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation. Conclusion: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms.

KW - Biofilm eradication

KW - Identified Javanese turmeric ethanol extract

KW - Porphyromonas gingivalis

KW - Streptococcus sanguinis

UR - http://www.scopus.com/inward/record.url?scp=85145824552&partnerID=8YFLogxK

U2 - 10.22159/ijap.2019.v11s1.155

DO - 10.22159/ijap.2019.v11s1.155

M3 - Article

AN - SCOPUS:85145824552

SN - 0975-7058

VL - 11

SP - 18

EP - 22

JO - International Journal of Applied Pharmaceutics

JF - International Journal of Applied Pharmaceutics

ER -

Efficacy of javanese turmeric ethanol extract in eradicating streptococcus sanguinis and porphyromonas gingivalis biofilm

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this