Effects of weekly iron supplementation on pregnant Indonesian women are similar to those of daily supplementation

Endi Ridwan, Werner Schultink, Drupadi Harnopidjati, Rainer Gross

Research output: Contribution to journalArticlepeer-review

100 Citations (Scopus)

Abstract

The effect of daily rather than weeky iron supplementation was compared in women who were 8-24 wk pregnant. One group (n = 68) received 60 mg Fe/d, the second group (n = 71) received 120 mg Fe/wk, given at once. Supplementation lasted 11.3 wk on average, depending on gestational date at entry, and was not supervised. Hemoglobin increased in both groups (P < 0.001); serum ferritin did not change significantly. There was no significant difference between groups for changes in hemoglobin and serum ferritin. In a subgroup of women with a hemoglobin concentration < 110 g/L at baseline (n = 45 daily; n = 54 weekly) no significant within-group changes occurred in serum ferritin, but the change in the daily group was 4.1 μg/L higher than in the weekly group (P = 0.049). Compliance, as indicated by two positive stool tests, was ≃54.3% in the daily group and 62.2% in the weekly group. We conclude that for the complete sample of subjects, the treatment effect of daily compared with weekly supplementation was similar under conditions resembling a normal antenatal care program.

Original languageEnglish
Pages (from-to)884-890
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume63
Issue number6
DOIs
Publication statusPublished - 1 Jan 1996

Keywords

  • Anemia
  • iron
  • pregnancy
  • weekly supplementation

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