Effects of soybean milk, chitosan, and anti-Streptococcus mutans IgY in malnourished rats' dental biofilm and the IgY persistency in saliva

Endang W. Bachtiar, Retno D. Soejoedono, Boy M. Bachtiar, Alisya Henrietta, Nur Farhana, Mindya Yuniastuti

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Objective: This study aims to evaluate the effect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva. Materials and Methods: Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY. Results: The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding. Conclusions: Soybean milk supplemented with anti-S. mutans IgY and chitosan could significantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats' saliva following the feeding period.

Original languageEnglish
Pages (from-to)118-123
Number of pages6
JournalInterventional Medicine and Applied Science
Volume7
Issue number3
DOIs
Publication statusPublished - Sept 2015

Keywords

  • Biofilm
  • Chitosan
  • IgY
  • S. mutans
  • Soy milk

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