Effects of Moderate-Intensity Exercise Training on Stress Oxidative Marker: Malondialdehyde and Superoxide Dismutase Activity in Abdominal Aorta of Juvenile Rats

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Abstract

To improve cardiovascular health, the WHO recommends 60 minutes of frequent moderate intensity physical activity in childhood. ACSM also recommends physical activity 30 minutes moderate activity or 30 minutes vigorous intensity, 3-4 times per week. However, limited data concerned in exercise starting from childhood effect to oxidative stress marker in vascular. Therefore the long-term effects of moderate intensity aerobic exercise training in early age on the cardiovascular, specifically on vascular stress oxidative marker needed to be studied. This study was conducted on male Wistar rats aged 3 weeks (60-70 grams), randomly allocated into 2 groups: 1) control group and 2) training group. Aerobic exercise training was conducted for 8 weeks on treadmill with age-dependent speeds. Training was intermittently 5 days each week for 20 minutes. Vascular oxidative stress marker was analyzed by measuring the level of malondialdehyde (MDA) and superoxide dismutase (SOD) activity on the abdominal aorta. Both the levels of MDA and SOD activity tended to increase in training group compared to the control group. The resuls of this study showed that long-term effects of moderate intensity aerobic exercise training in juvenile tended to increase the levels of MDA and specific SOD activity in the abdominal aorta tissues.
Original languageEnglish
Pages (from-to)99-105
JournalInternational Journal of Research - GRANTHAALAYAH
Volume5
Issue number12
DOIs
Publication statusPublished - 1 Dec 2017

Keywords

  • Moderate Intensity Aerobic Exercise Training; Juvenile, Stress Oxidative Marker, MDA, SOD, Abdominal Aorta

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