TY - JOUR
T1 - Effects of extra virgin olive oil versus rice bran oil on glycemic control in patients with type-2 diabetes mellitus
AU - Wijayanthie, Nadiyah
AU - Gunarti, Dwirini Retno
AU - Manikam, Nurul Ratna
AU - Yulhasri, null
N1 - Funding Information:
The present study was supported by a Publikasi Internasional Terindeks Untuk Tugas Akhir Mahasiswa (PITTA) grant (2018) provided by the Directorate of Research and Community Services Universitas Indonesia. The funders had no role in study design, data analysis/collection, decision to publish, or preparation of the manuscript.
Funding Information:
The present study was supported by a Publikasi Internasional Terindeks Untuk Tugas Akhir Mahasiswa (PITTA) grant (2018) provided by the Directorate of Research and Community Services Universitas Indonesia.
Publisher Copyright:
© 2019 The Authors. Published by Innovare Academic Sciences Pvt Ltd.
PY - 2019/11
Y1 - 2019/11
N2 - Objective: The purpose of this study was to determine the effect of extra virgin olive oil (EVOO) and rice bran oil (RBO) on glycemic control and lipid profiles in patients with type-2 diabetes mellitus (T2DM). Methods: Ten patients with T2DM received 15 ml/day of EVOO or RBO. Levels of fasting blood glucose (FBG), postprandial blood glucose (PBG), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and triglycerides (TGs) were measured. RBO or EVOO was administered for 4 consecutive weeks. During a 2-week interval, the treatment was not administered. After this washout period, a crossover design was implemented by exchanging EVOO supplementation with RBO supplementation and vice versa for 4 consecutive weeks. Results: Changes in levels of FBG, PBG, TC, LDL-C, and TGs were not significantly different in the two groups. However, significantly decreased the levels of HDL-C were observed in both groups. Conclusion: RBO and EVOO had no significant influence on levels of FBG or PBG.
AB - Objective: The purpose of this study was to determine the effect of extra virgin olive oil (EVOO) and rice bran oil (RBO) on glycemic control and lipid profiles in patients with type-2 diabetes mellitus (T2DM). Methods: Ten patients with T2DM received 15 ml/day of EVOO or RBO. Levels of fasting blood glucose (FBG), postprandial blood glucose (PBG), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and triglycerides (TGs) were measured. RBO or EVOO was administered for 4 consecutive weeks. During a 2-week interval, the treatment was not administered. After this washout period, a crossover design was implemented by exchanging EVOO supplementation with RBO supplementation and vice versa for 4 consecutive weeks. Results: Changes in levels of FBG, PBG, TC, LDL-C, and TGs were not significantly different in the two groups. However, significantly decreased the levels of HDL-C were observed in both groups. Conclusion: RBO and EVOO had no significant influence on levels of FBG or PBG.
KW - Glucose level
KW - Lipid level
KW - Olive oil
KW - Rice bran oil
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=85077144201&partnerID=8YFLogxK
U2 - 10.22159/ijap.2019.v11s6.33540
DO - 10.22159/ijap.2019.v11s6.33540
M3 - Article
AN - SCOPUS:85077144201
SN - 0975-7058
VL - 11
SP - 56
EP - 59
JO - International Journal of Applied Pharmaceutics
JF - International Journal of Applied Pharmaceutics
IS - Special Issue 6
ER -
