Effectiveness of water as the neutralising agent for glycolic acid peels in skin phototypes IV-V

Irma Bernadette S. Sitohang, Githa Rahmayunita, Vashty Amanda Hosfiar, Shafira Ninditya, Maureen Augustin

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of the study is to evaluate the effectiveness of water as a substitute for sodium bicarbonate plus solution in the neutralisation process of chemical peeling using a 35% glycolic acid solution. This randomised, double-blind, split-face, controlled trial was conducted in an outpatient setting. A total of 126 healthy patients with skin phototypes IV–V aged between 18 and 60 years old were recruited. Chemical peeling was performed with 35% glycolic acid solution. One side of the face was neutralised with water, and the other side of the face was neutralised with a sodium bicarbonate plus solution. The main outcome of this study was measured by the degree of erythema, pruritus and pain scores. Significant difference in the pain score immediately after the neutralisation process of the chemical peeling with glycolic acid was seen. However, there were no significant differences in the degree of erythema or the pruritus score. These results indicate that water can be used as a substitute for sodium bicarbonate plus solution in the neutralisation process of chemical peeling with 35% glycolic acid in patients with skin phototypes IV–V.

Original languageEnglish
JournalAustralasian Journal of Dermatology
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • chemexfoliation
  • glycolic acid peel
  • skin phototypes IV–V
  • sodium bicarbonate
  • split face
  • water

Fingerprint

Dive into the research topics of 'Effectiveness of water as the neutralising agent for glycolic acid peels in skin phototypes IV-V'. Together they form a unique fingerprint.

Cite this