TY - JOUR
T1 - Effectiveness of identified javanese turmeric ethanol extract for the inhibition of biofilm formation by streptococcus mutans and porphyromonas gingivalis
AU - Marpaung, Liza Noah Febriana
AU - Suniarti, Dewi Fatma
AU - Sarwono, Agoeng Tjahajani
N1 - Publisher Copyright:
© 2019 The Authors.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - Objective: To study the effectiveness of identified Javanese turmeric ethanol extract (IJTEE) against single and combined biofilm formation by Streptococcus mutans and Porphyromonas gingivalis. Methods: S. mutans ATCC 25175 and P. gingivalis ATCC 33277 were tested for the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of IJTEE using microdilution technique. The inhibition of biofilm formation by IJTEE was analyzed using crystal violet assay. Results: MIC and MBC of IJTEE for S. mutans were 5% and 15%, respectively. MIC of IJTEE for the biofilm of S. mutans was 1% and for that of P. gingivalis was 15%; the MIC of IJTEE for the combined biofilm was 0.5%. Conclusion: IJTEE was effective in inhibiting single and combined biofilm formation by S. mutans and P. gingivalis.
AB - Objective: To study the effectiveness of identified Javanese turmeric ethanol extract (IJTEE) against single and combined biofilm formation by Streptococcus mutans and Porphyromonas gingivalis. Methods: S. mutans ATCC 25175 and P. gingivalis ATCC 33277 were tested for the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of IJTEE using microdilution technique. The inhibition of biofilm formation by IJTEE was analyzed using crystal violet assay. Results: MIC and MBC of IJTEE for S. mutans were 5% and 15%, respectively. MIC of IJTEE for the biofilm of S. mutans was 1% and for that of P. gingivalis was 15%; the MIC of IJTEE for the combined biofilm was 0.5%. Conclusion: IJTEE was effective in inhibiting single and combined biofilm formation by S. mutans and P. gingivalis.
KW - Biofilm
KW - Identified Javanese turmeric ethanol extract
KW - Minimum bactericidal concentration
KW - Minimum inhibitory concentration
KW - Porphyromonas gingivalis
KW - Streptococcus mutans
UR - http://www.scopus.com/inward/record.url?scp=85067940692&partnerID=8YFLogxK
U2 - 10.22159/ijap.2019.v11s1.156
DO - 10.22159/ijap.2019.v11s1.156
M3 - Article
AN - SCOPUS:85067940692
SN - 0975-7058
VL - 11
SP - 23
EP - 26
JO - International Journal of Applied Pharmaceutics
JF - International Journal of Applied Pharmaceutics
ER -