Effect of white tea extract In Vitro against cariogenic and periodontal bacteria

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Objective: This work aimed to evaluate the in vitro antimicrobial properties of white tea maceration extract against pathogenic oral bacteria Streptococcus mutans (serotype F), Porphyromonas gingivalis (strain ATCC 33277), and Actinobacillus actinomycetemcomitans (phenotype A); the properties of this product were also tested against non-pathogenic Streptococcus sanguis (ATCC 10556) for comparison. Methods: A maceration extract was made from white tea collected from West Java, and the infusion was prepared at concentrations of 5-80%. The selected strains of each microbial species were cultured under anaerobic conditions, and equalized standard dilutions of the cultured bacteria were used for testing. Dilution and diffusion tests were conducted to quantify the antimicrobial properties of white tea extract (WTE) against the bacteria. Results: The dilution test results showed a minimum inhibitory concentration of 40% of WTE against S. mutans, P. gingivalis, and A. actinomycetemcomitans and 80% against S. sanguis. The minimum bactericidal concentration was 80% for all tested bacterial strains. Conclusion: The diffusion test results showed higher inhibition with increasing extract concentration; however, the difference between concentrations of 40% and 80% was small or negligible, except for A. actinomycetemcomitans. These results imply the clear, acute antimicrobial effect of WTE against the tested oral anaerobic pathogens in vitro. Considering that these effects were concentration dependent and that white tea has the highest content of antimicrobial phenolic compounds among all grades of (green) tea, white tea or WTE may be useful for inhibiting the growth of pathogens involved in the development of caries and/or periodontal disease.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalInternational Journal of Applied Pharmaceutics
Issue numberSpecial Issue 1
Publication statusPublished - 1 Dec 2018


  • Antimicrobial
  • Cariogenic bacteria
  • Periodontal bacteria
  • White tea extract


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