Effect of topical anti-Streptococcus mutans IgY gel on quantity of S. mutans on rats' tooth surface

Endang Winiati, Anggraeni Afdhal, Ratna Meidyawati, Retno D. Soejoedono, Erni Hernawati Purwaningsih

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This study aims to evaluate the effect of anti-Streptococcus mutans IgY gel on quantity of S. mutans on rats' tooth surface. Sprague Dawley rats were exposed intraorally with S. mutans Xc and were fed a caries-inducing diet 2000. The 24 rats were divided into four groups: group A had their teeth coated with IgY gel; group B received sterilized water as a control; group C had their teeth coated with IgY gel starting on the 29th day; and group D had their teeth coated with a gel without IgY. Plaque samples were swabbed from the anterior teeth for S. mutans colony quantification, and saliva was collected to measure immunoreactivity by enzyme-linked immunosorbent assay. The results indicated that the quantity of S. mutans in rats treated with IgY gel showed significant difference compared with the controls. After coating with IgY anti-S. mutans gel, the mean immunoreactivity in rat saliva was higher than that of the no treatment group. In conclusion, topical application with anti-S. mutans IgY gel reduced the quantity of S. mutans on the tooth surface.

Original languageEnglish
Pages (from-to)159-169
Number of pages11
JournalActa Microbiologica et Immunologica Hungarica
Volume63
Issue number2
DOIs
Publication statusPublished - 1 Jun 2016

Keywords

  • Caries
  • IgY gel
  • S. mutans

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