Effect of Plasticizer on Malleability of Polylactide-Based Craniomaxillofacial Fracture Fixation Plates

R. Setyo Adji Koesoemowidodo, Azizah Intan Pangesty, Yudan Whulanza, Sugeng Supriadi, Mochamad Chalid, Sunarso, Abdul Halim Abdullah

Research output: Contribution to journalConference articlepeer-review


In this study, the effect of plasticization on the malleability of polylactide-based implant plates in craniomaxillofacial bone fracture application was studied. Specimens were synthesized by adding a plasticizer with a concentration of 2wt% in a mixture of PLLA and PDLLA (70:30). The mixing process was carried out by rheo-mixing, and the forming process was utilized in a vacuum oven. Specimens were characterized to determine their properties. The addition of glycerol and PEG 400 plasticizer influenced the shift in the absorbance of the infrared spectra. Furthermore, the plasticizer lowered the glass transition temperature (Tg) from 62.3°C to 58.5°C. The bending strength, bending strain, and modulus of elasticity of the specimens were also reduced. Microstructural analysis evaluation showed that the mixture was miscible. The results of the degradation test showed that the plasticized specimen 30PDLLA/glycerol underwent a degradation process with the smallest portion.

Original languageEnglish
Article number130002
JournalAIP Conference Proceedings
Issue number1
Publication statusPublished - 7 Mar 2024
Event15th Asian Congress on Biotechnology in conjunction with the 7th International Symposium on Biomedical Engineering, ACB-ISBE 2022 - Bali, Indonesia
Duration: 2 Oct 20226 Oct 2022


  • CMF
  • glycerol implant
  • PEG400
  • PLA
  • plasticizer
  • polylactide


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