Effect of mouthrinse containing immunoglobulin-y anti-comd streptococcus mutans + chitosan on quantity of salivary streptococcus mutans in caries and caries-free subjects

Endang Winiati Bachtiar, Adani Nur Imanina, Retno D. Soejoedono, I. Wayan Teguh Wibawan

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Immunoglobulin-Y (IgY) anti-ComD Streptococcus mutans is expected to be an alternative passive immunization agent against caries. Chitosan which has an antibacterial property is expected to produce a better result. The aim of this study is to evaluate the effect of mouthrinse containing IgY anti-ComD S. mutans + chitosan on the quantity of salivary S. mutans in caries and caries-free subjects. Methods: Each subject group was given IgY anti-ComD S. mutans mouthrinse and IgY anti-ComD S. mutans + chitosan mouthrinse. Mouthrinse was used twice a day for 6 days. Salivary S. mutans was cultured in TYS20B agar before and after treatment. The quantity of salivary S. mutans colonies was counted manually. Results: This study showed that mouthrinse containing IgY anti-ComD S. mutans + chitosan has the potential to decrease the quantity of salivary S. mutans although not significantly.

Original languageEnglish
Pages (from-to)120-122
Number of pages3
JournalInternational Journal of Applied Pharmaceutics
Volume11
DOIs
Publication statusPublished - 1 Apr 2019

Keywords

  • Caries
  • Chitosan
  • ComD protein
  • Immunoglobulin Y
  • Mouthrinse

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