Objective: Immunoglobulin-Y (IgY) anti-ComD Streptococcus mutans is expected to be an alternative passive immunization agent against caries. Chitosan which has an antibacterial property is expected to produce a better result. The aim of this study is to evaluate the effect of mouthrinse containing IgY anti-ComD S. mutans + chitosan on the quantity of salivary S. mutans in caries and caries-free subjects. Methods: Each subject group was given IgY anti-ComD S. mutans mouthrinse and IgY anti-ComD S. mutans + chitosan mouthrinse. Mouthrinse was used twice a day for 6 days. Salivary S. mutans was cultured in TYS20B agar before and after treatment. The quantity of salivary S. mutans colonies was counted manually. Results: This study showed that mouthrinse containing IgY anti-ComD S. mutans + chitosan has the potential to decrease the quantity of salivary S. mutans although not significantly.
- ComD protein
- Immunoglobulin Y