Effect of grape seed extract against biodegradation of composite resin-dentin shear bond strength

This study aimed to analyze the effect of grape seed extract (GSE) on resin-dentin shear bond strength. A group of 48 dentin samples were divided into 6 groups. The six groups, each with eight specimens, included group 1 (control), group 2 (control + NaOCl 10%), group 3 (2.9% GSE application before etching), group 4 (2.9% GSE application before etching + NaOCl 10%), group 5 (2.9% GSE application after etching), and group 6 (2.9% GSE application after etching + NaOCl 10%). Shear bond strengths were measured using a universal testing machine. Statistical analysis was done with the Kruskal-Wallis test and the Mann-Whitney U test. The highest median value was in group 3, and the lowest value was in group 5. GSE can improve the shear bond strength (p = 0.002 and 0.001), but it has no effect on reducing biodegradation (p = 0.141).