Effect of Aerobic exercise and high intensity interval training on relative Leukocyte telomere length in Sprague Dawley rats

Dewi Irawati Soeria Santoso, Nurul Paramita, Septelia Inawati Wanandi, Swandito Wicaksono, Thressia Hendrawan

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to compare the effect of High Intensity Interval Training (HIIT) versus Aerobic Exercise (A-Ex) following 12 wks of training. Twenty-one Sprague Dawley rats (11 to 13 months) were assigned to 3 groups: (1) Control Group (no exercise); (2) A-Ex Group; and (3) HIIT Group. The A-Ex Group was submitted to treadmill exercise at a speed of 20 m·min-1 with a rest period of 90 sec every 5 min for 20 min 5 d·wk-1. The HIIT Group was submitted to treadmill exercise at a speed of 35 m·min-1 with a rest period of 90 sec every 5 min for 15 min 5 d·wk-1. At weeks 4 and 12, relative Leukocyte Telomere Length (LTL) was compared to week 4 of the Control Group using q-RT-PCR. It was shown that relative LTL in the A-Ex Group at week 4 and 12 was significantly longer compared to week 4 of the Control Group (P < 0.05), but no significant difference in the HIIT Group compared to the Control Group (P > 0.05). We concluded that 12 wks of aerobic and HIIT exercise both cause lengthening of relative LTL. Aerobic exercise has a better effect compared to HIIT in relation to changes in relative LTL.

Original languageEnglish
Pages (from-to)116-123
Number of pages8
JournalJournal of Exercise Physiology Online
Volume22
Issue number3
Publication statusPublished - 1 Jun 2019

Keywords

  • Aerobic Exercise
  • High Intensity Interval Training
  • Leukocyte Telomere Length

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