Efektifitas Pemberian Proton Pump Inhibitor pada Bayi dan Anak dengan Laringomalasia

Riza Sahyuni, Bambang Supriyatno, Syahrial M Hutauruk, Aria Kekalih

Research output: Contribution to journalArticlepeer-review


laryngomalacia is condition of floopy supraglottis stucture and it causes symptom stridor. In general, the comorbidity of laryngomalacia is laryngopharyngeal reflux (LPR). The giving of omeperazole can improve the symptom of regurgitation and stridor and shorten the duration of natural disease of laryngomalacia. Objective. Knowing the effectivity of giving omeperazole to the babies and children with laryngomalacia. Method. Test pre-post experimental on 42 samples that have been given omeperazole 2x2 mg/kg/bw for 3 month. Result. Giving omeperazol on laryngomalacia with severe symptom showed the improvement of 58,8%. Giving omeperazole on laryngomalacia with RLF positive showed the improvement of 58,3%. Seemed statistically significant improvement in comparison pre and post score reflux finding score (RFS) and laringomalacia score symptom (LSS). Conclusion. The Prevalence of positive LPR based on RFS is 24,6% and with severe symptom is 44,6%. The effectivity of giving omeperazole for 3 month has proved effective based on the improvement of value LSS, RFS and nutrition status.
Original languageIndonesian
Pages (from-to)459-467
JournalSari Pediatri
Issue number6
Publication statusPublished - 1 Apr 2017


  • laryngopharyngeal reflux (LPR), reflux finding score (RFS), laryngomalacia symptom score (LSS), laryngomalacia

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