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Every drug can produce side effect, even when used according to standard or recommended methods of administration.Side effect of drugs can involve every organ and system of the body and are frequently mistaken for signs of underlying disease. Similarly, the mouth and associated structures can be affected by many drugs or chemicals. Good oral health including salivary function is very important in maintaining whole body health. Certain drugs can cause change in the oral cavity. Intrinsic discoloration can occur with the tertracyclines and extrisic stains are associated with certain metal containing liquids. Ginigival hyperplasia can occur with some anticonvulstants, calcium channel blockers, and cyclosporine. Xerostomia are produced by hypertensives, antipsikosis, antihistamin, antikolinergik and many other drugs. Regarding different parts of the oral system, drug side effects can be categorized to oral mucosa and tongue, periodontal tissue, dental structures, salivary glands, cleft lip and palate, muscular and neurological disorders, taste disturbances and drug-induced oral infection. The knowledge about drug-induced oral side effects helps dentist and to better diagnose oral disease, administer drugs, improve patient compliance during drug therapy, and may influence a more rational use of drugs.
Original languageIndonesian
JournalJournal of Dentistry Indonesia
Publication statusPublished - 2003

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