Drug use pattern in dengue patients who visited hospitals and primary health center in Yogyakarta, Indonesia

Erna Kristin, Alfi Yasmina, Rizaldy Taslim Pinzon, Woro Rukmi Pratiwi, Christiana Trijayanti, Ery Setiawan, Vettyyulianti Permanasari, Mardiati Nadjib

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Studies on the pattern of drug utilization for the treatment of dengue in Indonesia are lacking. The objective of this study was to assess the use of drug treatment for dengue in several hospitals and primary health center (PHC) in Yogyakarta, Indonesia. A retrospective study was conducted on 239 dengue patients in selected hospitals or PHC between April 1st, 2014 and March 31st, 2015. Patients who were clinically diagnosed/laboratory confirmed as dengue with evidence of fever for more than 1 day (plus one of the World Health Organization dengue symptoms) were included. Information on patients’ characteristics was gathered from medical records, while drug use data were collected from the prescriptions records. These data were analyzed descriptively. An average of 4.16±2.16 drugs was prescribed per prescription in the hospital, and 2.48±1.21 drugs were prescribed per prescription in PHC. There were 71.6% drugs prescribed in the hospital and 92.7% drugs prescribed in PHC included in the National Formulary. Generics were prescribed in 39.4% and 95.4% drugs in the hospital and PHC, respectively. The most commonly prescribed drugs were analgesics (26.3%), vitamins (14.2%), drugs for acid-related disorders (11.7%), and systemic antibacterials (10.2%). Systemic corticosteroids were prescribed in 6.0% patients. In conclusion, the treatment of dengue patients who visited the hospitals and PHC in Yogyakarta, Indonesia, was rational in some aspects. However, antibiotics and corticosteroids were still used, and positive changes and improvements are needed to increase the rational drug use in dengue patients.

Original languageEnglish
Pages (from-to)2065-2068
Number of pages4
JournalJournal of Pharmaceutical Sciences and Research
Issue number8
Publication statusPublished - Aug 2018


  • Antibiotic
  • Corticosteroid
  • Dengue
  • Treatment


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