High power consumption in piping system due to high pressure losses in a turbulent flow has been recognized as a critical problem occurring to fluid flows in various industrial piping systems, including crude oil transportation in the oil and gas sector. To solve the problem, a drag reducing agent (DRA) is added into crude oil flow for improving the pumping efficiency. One of most technically effective, low costs and well-known DRA is anionic surfactant. Thus, this study aims at investigating the reduction of pressure drop by adding anionic surfactant sodium lauryl sulfate (SLS) at different concentrations into crude oil flow in a pentagon spiral pipe. Effectiveness of the DRA is comparatively observed in a pentagon spiral pipe with 10.8 ratio of diameter (P/Di) and in a circular pipe with 4mm inner diameter. This research particularly highlights the application of pentagon spiral pipe to provide the maximum drag reduction performance for crude oil flow. Then, a certain concentration of anionic surfactant SLS is observed to actively reduce friction factor.