Diskrepansi Nilai CRP dan LED pada Fase Akut Penyakit Kawasaki

Background. The diagnosis of Kawasaki disease (KD) according to the AHA statements 2004 and 2017 is based on clinical findings. Laboratory tests, especially acute phase reactans such as CRP and ESR are useful to support the diagnosis. The degree of elevation of ESR (erythrocyte sedimentation rate) and CRP (C reactive protein) may be discrepant as shown by a previous study. Objective. To determine whether it is necessary to examine both CRP and ESR or either of them at acute stage of Kawasaki disease Methods. We did a retrospective study on 1163 subjects with KD which were taken consecutively from 1 st April 2000 untill 31 st May 2017. There were 741subjects with complete medical records. We used the cut off point of CRP > 30 mg/dL, and ESR > 40 mm to be categorized as elevated. Results. There were 30.8% subjects with discrepancy between their CRP and ESR results, which means elevated CRP with normal ESR or vice versa. Conclusion. Both CRP and ESR need to be examined at acute stage of KD.