TY - JOUR
T1 - Direct electrochemical detection of sodium azide in physiological saline buffers using highly boron-doped diamond electrodes
AU - Suzuki, Akane
AU - Anggraningrum, Ivandini Tribidasari
AU - Kamiya, Akihide
AU - Nomura, Satoshi
AU - Yamanuki, Mikito
AU - Matsumoto, Koichi
AU - Fujishima, Akira
AU - Einaga, Yasuaki
N1 - Funding Information:
Tribidasari Anggraningrum Ivandini received her Ph.D. from The University of Tokyo in 2003. She is a lecturer in the Department of Chemistry, Mathematics and Science Faculty, University of Indonesia in Jakarta, Indonesia. Now, she is doing post-doctoral research supported by JSPS award at Chemistry Department, Keio University, Japan. Her interest is in diamond electrochemistry.
PY - 2007/1/10
Y1 - 2007/1/10
N2 - Direct detection of sodium azide was examined by using highly boron-doped diamond (BDD) electrodes in some physiological saline buffer solutions. Three important saline buffers, ADA buffer (N-(2-acetamido) iminodiacetic acid), sodium EDTA and imidazole, were investigated. Hydrogen-terminated BDD was fixed for the investigation since it showed much better sensitivity for azide oxidation in comparison with the oxygen-terminated one. Wide range of buffer concentration was examined. A well-separated peak of sodium azide was observed in its mixture with the buffers, resulting in selective sodium azide detection. The current responses were exactly total addition of sodium azide and buffer current responses. The present method was evidenced to be available for direct detection of sodium azide in two samples of commercial diluents for cell counting. A standard addition method was applied. Sodium azide concentrations of 502 and 1355 μg mL-1 were detected in both samples with the R.S.D.s of 0.07 and 2.37%, respectively. Validation was achieved by the comparison with the sample concentrations given by the manufacturer. Simple, selective, good sensitivity and excellent reproducible detection make the diamond electrodes very attractive for numerous electroanalytical applications.
AB - Direct detection of sodium azide was examined by using highly boron-doped diamond (BDD) electrodes in some physiological saline buffer solutions. Three important saline buffers, ADA buffer (N-(2-acetamido) iminodiacetic acid), sodium EDTA and imidazole, were investigated. Hydrogen-terminated BDD was fixed for the investigation since it showed much better sensitivity for azide oxidation in comparison with the oxygen-terminated one. Wide range of buffer concentration was examined. A well-separated peak of sodium azide was observed in its mixture with the buffers, resulting in selective sodium azide detection. The current responses were exactly total addition of sodium azide and buffer current responses. The present method was evidenced to be available for direct detection of sodium azide in two samples of commercial diluents for cell counting. A standard addition method was applied. Sodium azide concentrations of 502 and 1355 μg mL-1 were detected in both samples with the R.S.D.s of 0.07 and 2.37%, respectively. Validation was achieved by the comparison with the sample concentrations given by the manufacturer. Simple, selective, good sensitivity and excellent reproducible detection make the diamond electrodes very attractive for numerous electroanalytical applications.
KW - Boron-doped diamond electrodes
KW - Cyclic voltammetry
KW - Physiological saline buffer
KW - Sodium azide
KW - Surface termination
UR - http://www.scopus.com/inward/record.url?scp=33845616227&partnerID=8YFLogxK
U2 - 10.1016/j.snb.2006.03.003
DO - 10.1016/j.snb.2006.03.003
M3 - Article
AN - SCOPUS:33845616227
SN - 0925-4005
VL - 120
SP - 500
EP - 507
JO - Sensors and Actuators, B: Chemical
JF - Sensors and Actuators, B: Chemical
IS - 2
ER -