Difuzní velkobuněčný B-lymfom asociovaný s ileocekální intususcepcí v dospělosti

Translated title of the contribution: Diffuse large B-cell lymphoma associated ileocecal intussusception in adulthood

Research output: Contribution to journalArticlepeer-review


Background: Intussusception in adults is considered a rare condition, accounting for 5% of all cases of intussusceptions and approx. 1–5% of bowel obstruction. Almost half intussusceptions of the bowel are associated with malignant disease; thus, we should also treat the underlying malignancy. Case description: A 52-year-old male presented with colicky right lower abdominal pain for a 6-month period. He had a weight loss of 20 kg within 6 months. Physical examination revealed a tender right lower abdominal mass. Colonoscopy showed a mass that filled the ileocecal. The digestive surgeon performed laparoscopic right hemicolectomy with end-to-end anastomosis. Histopathology examination showed diffuse proliferation of large tumor cells with centroblastic-like features prominently in submucosal area, with normal epithelial mucosa. The immunohistochemistry result concluded the final diagnosis of diffuse large B-cell lymphoma. RCHOP chemotherapy regimens were administered every 3 weeks for 6 cycles. The response was complete remission. Discussion: Intussusception was preoperatively diagnosed by multi-slice spiral CT scans with the characteristic target or sausage sign, edematous bowel wall and mesentery in the lumen. After surgery, approximately 90% of adult intussusception cases have a demonstrable etiology. Malignant lymphoma, especially diffuse large B-cell lymphoma, of the ileocecal is one cause of the adult intussusception. Conclusion: Adult bowel intussusception is a rare clinical entity. Abdominal CT is considered as the most sensitive imaging modality in the diagnosis of intussusception. Diffuse large B-cell lymphoma is the most common cause of ileocecal intussusception.

Translated title of the contributionDiffuse large B-cell lymphoma associated ileocecal intussusception in adulthood
Original languageCzech
Pages (from-to)236-239
Number of pages4
JournalKlinicka Onkologie
Issue number3
Publication statusPublished - 2022


  • bowel obstruction
  • diffuse large B-cell lymphoma
  • intussusception
  • malignant lymphoma


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