TY - JOUR
T1 - Diffuse Large B-Cell Lymphoma and Job’s Syndrome: A Case Report
AU - Cahyanur, Rahmat
AU - Rahmawati, Sari
PY - 2020
Y1 - 2020
N2 - Job’s syndrome or hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency. Characterized by recurrent pulmonary and skin infections with elevated IgE serum level, this syndrome has been considered a risk factor for lymphoma. Although the majority of cases were diagnosed in childhood, there are still a few cases that were diagnosed in adulthood. It is necessary to recognize these two conditions since the treatment for lymphoma patients with HIES should be adjusted and needs a thorough care. Here we present a case of diffuse large B cell lymphoma in a patient with symptoms of HIES diagnosed during chemotherapy.
AB - Job’s syndrome or hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency. Characterized by recurrent pulmonary and skin infections with elevated IgE serum level, this syndrome has been considered a risk factor for lymphoma. Although the majority of cases were diagnosed in childhood, there are still a few cases that were diagnosed in adulthood. It is necessary to recognize these two conditions since the treatment for lymphoma patients with HIES should be adjusted and needs a thorough care. Here we present a case of diffuse large B cell lymphoma in a patient with symptoms of HIES diagnosed during chemotherapy.
U2 - 10.26574/maedica.2020.15.2.269
DO - 10.26574/maedica.2020.15.2.269
M3 - Article
SN - 1841-9038
VL - 15
JO - Maedica A Journal of Clinical Medicine Bucharest
JF - Maedica A Journal of Clinical Medicine Bucharest
IS - 2
ER -