TY - JOUR
T1 - Diagnosis and management of latent tuberculosis infection in Asia
T2 - Review of current status and challenges
AU - Paton, Nicholas I.
AU - Borand, Laurence
AU - Benedicto, Jubert
AU - Kyi, Mar Mar
AU - Mahmud, Asif Mujtaba
AU - Norazmi, Mohd Nor
AU - Sharma, Nandini
AU - Chuchottaworn, Charoen
AU - Huang, Yi Wen
AU - Kaswandani, Nastiti
AU - Le Van, Hoi
AU - Lui, Grace C.Y.
AU - Mao, Tan Eang
N1 - Funding Information:
The expert panel meeting and medical writing support for the development of the position paper was funded by an educational grant by Sanofi-Aventis. Sanofi was not involved in the discussions of the expert panel members and had no role in the writing of the position paper.We would like to thank Dr. Noorliza Mohd Noordin, Ministry of Health, and the Ministry of Education (for the LRGS grant), Malaysia for providing relevant regional inputs for the development of this position paper. We would also like to thank BioQuest Solutions Pvt. Ltd. for the medical writing and editorial support for the development of this position paper.
Publisher Copyright:
© 2019
PY - 2019/10
Y1 - 2019/10
N2 - Asia has the highest burden of tuberculosis (TB) and latent TB infection (LTBI) in the world. Optimizing the diagnosis and treatment of LTBI is one of the key strategies for achieving the WHO ‘End TB’ targets. We report the discussions from the Asia Latent TubERculosis (ALTER) expert panel meeting held in 2018 in Singapore. In this meeting, a group of 13 TB experts from Bangladesh, Cambodia, Hong Kong, India, Indonesia, Malaysia, Myanmar, the Philippines, Singapore, Taiwan, Thailand and Vietnam convened to review the literature, discuss the barriers and propose strategies to improve the management of LTBI in Asia. Strategies for the optimization of risk group prioritization, diagnosis, treatment, and research of LTBI are reported. The perspectives presented herein, may help national programs and professional societies of the respective countries enhance the adoption of the WHO guidelines, scale-up the implementation of national guidelines based on the regional needs, and provide optimal guidance to clinicians for the programmatic management of LTBI.
AB - Asia has the highest burden of tuberculosis (TB) and latent TB infection (LTBI) in the world. Optimizing the diagnosis and treatment of LTBI is one of the key strategies for achieving the WHO ‘End TB’ targets. We report the discussions from the Asia Latent TubERculosis (ALTER) expert panel meeting held in 2018 in Singapore. In this meeting, a group of 13 TB experts from Bangladesh, Cambodia, Hong Kong, India, Indonesia, Malaysia, Myanmar, the Philippines, Singapore, Taiwan, Thailand and Vietnam convened to review the literature, discuss the barriers and propose strategies to improve the management of LTBI in Asia. Strategies for the optimization of risk group prioritization, diagnosis, treatment, and research of LTBI are reported. The perspectives presented herein, may help national programs and professional societies of the respective countries enhance the adoption of the WHO guidelines, scale-up the implementation of national guidelines based on the regional needs, and provide optimal guidance to clinicians for the programmatic management of LTBI.
KW - Asia
KW - Awareness
KW - Latent tuberculosis infection
KW - Optimization
UR - http://www.scopus.com/inward/record.url?scp=85071243326&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2019.07.004
DO - 10.1016/j.ijid.2019.07.004
M3 - Review article
C2 - 31301458
AN - SCOPUS:85071243326
SN - 1201-9712
VL - 87
SP - 21
EP - 29
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -
