Diagnosis and management of acromegaly: giant invasive adenoma.

Rahmat Cahyanur, Wawan Setyawan, Dedy G. Sudrajat, Susie Setyowati, Rr. Dyah Purnamasari Sulistianingsih, Pradana Soewondo

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Acromegaly is a rare disorder caused by excessive growth hormone. Majority of acromegaly are due to pituitary adenoma. It is estimated that 5% of pituitary adenoma become invasive and may grow to gigantic sizes (>4 cm in diameter). We would like to describe a man with giant invasive adenoma. We describe the case of 52-year-old man with acromegaly. The patient was presented to medical care because of hemichorea. He also had visual field defect, uncontrolled diabetes, and dyslipidemia. Hormonal profile showed increment of GH 2-hour after a standard 75-g oral glucose load and of high IGF-1 level with low level of FSH and LH. The next was performed by pituitary imaging. Magnetic resonance imaging showed a macroadenoma with diameter 2.3x3.5x6.6 cm3 that fills the sella tursica, and enlarges into suprasella, genu of corpus collosum, and invades third ventricle. This report describes a rare case of acromegalic patient with giant invasive adenoma. This could be a demonstrative case and lesson for diagnosis and manage acromegalic patient.

Original languageEnglish
Pages (from-to)122-128
Number of pages7
JournalActa medica Indonesiana
Issue number2
Publication statusPublished - Apr 2011


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