Development of Electrochemical Glutamate Biosensor: A Review

Nurul Dwi Syafitri, Atya Saniah, Nurul Intan, Yudan Whulanza, Siti Fauziyah Rahman

Research output: Contribution to journalConference articlepeer-review

Abstract

One neurotransmitter, glutamate, is crucial for the development and maintenance of synapses as well as for the processes of consciousness, memory, and learning. Abnormal levels of glutamate in the body can lead to various risks of neurological diseases. The existing tools for detecting glutamate levels have several drawbacks. They are time-consuming and expensive. Besides that, less research or development has been done on glutamate biosensors than on other types of biosensors. In this review, the development of electrochemical glutamate biosensors was discussed. A review of the analyte, enzymes used, immobilization techniques, materials used, and analysis findings regarding linear range, detection limit, and sensitivity has been performed in order to develop a glutamate biosensor. The non-enzymatic electrochemical glutamate sensor can continue to be developed for promising enzyme-free glutamate biosensors.

Original languageEnglish
Article number110006
JournalAIP Conference Proceedings
Volume3080
Issue number1
DOIs
Publication statusPublished - 7 Mar 2024
Event15th Asian Congress on Biotechnology in conjunction with the 7th International Symposium on Biomedical Engineering, ACB-ISBE 2022 - Bali, Indonesia
Duration: 2 Oct 20226 Oct 2022

Keywords

  • biosensor
  • electrochemical
  • glutamate
  • neurotransmitter

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