Determination of in vivo immunomodulatory activity of mixed herbs extracts using total protein serum and depiction of lymphatic organ

Dewi Tristantini, Adeline Jessica

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Immunomodulator had a role in improving function and restoring the balance of the immune system. Research of immunomodulatory activity had been conducted and studied. Mimusops elengi leaves, Averrhoa carambola leaves and Curcuma xanthorrhiza rhizomes were mixed. The herbs were processed into a particle size. Various tests were performed to 5 groups of -white male rats. They were divided to the normal group (without treatment), positive control group induced with Imboost and 3 groups induced with various dose of herbs extract. The research showed mean total serum protein for regular group, the positive control group, dosage 1, 2, and 3 groups 8.56; 9.26; 9.71; 9.74 and 9.74g/dL, respectively. For a number of white pulp in the spleen, normal group, positive control, dosage 1, 2, and 3 groups resulted in 29, 27, 26, 27, and 20, respectively. These results indicated regulation with an inflammatory reaction. The mixed herbs extract developed its immunomodulatory activity after inducement.

Original languageEnglish
Title of host publication3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2018
EditorsPraswasti P.D.K. Wulan, Misri Gozan, Sotya Astutiningsih, Ghiska Ramahdita, Radon Dhelika, Prasetyanugraheni Kreshanti
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418226
DOIs
Publication statusPublished - 9 Apr 2019
Event3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018 - Jakarta, Indonesia
Duration: 6 Aug 20188 Aug 2018

Publication series

NameAIP Conference Proceedings
Volume2092
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
CountryIndonesia
CityJakarta
Period6/08/188/08/18

Keywords

  • Averrhoa carambola
  • Curcuma xanthorrhiza
  • Histopathological Study
  • Immunomodulatory Activity
  • Mimusops elengi

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