TY - GEN
T1 - Determination of in vivo immunomodulatory activity of mixed herbs extracts using total protein serum and depiction of lymphatic organ
AU - Tristantini, Dewi
AU - Jessica, Adeline
N1 - Publisher Copyright:
© 2019 Author(s).
PY - 2019/4/9
Y1 - 2019/4/9
N2 - Immunomodulator had a role in improving function and restoring the balance of the immune system. Research of immunomodulatory activity had been conducted and studied. Mimusops elengi leaves, Averrhoa carambola leaves and Curcuma xanthorrhiza rhizomes were mixed. The herbs were processed into a particle size. Various tests were performed to 5 groups of -white male rats. They were divided to the normal group (without treatment), positive control group induced with Imboost and 3 groups induced with various dose of herbs extract. The research showed mean total serum protein for regular group, the positive control group, dosage 1, 2, and 3 groups 8.56; 9.26; 9.71; 9.74 and 9.74g/dL, respectively. For a number of white pulp in the spleen, normal group, positive control, dosage 1, 2, and 3 groups resulted in 29, 27, 26, 27, and 20, respectively. These results indicated regulation with an inflammatory reaction. The mixed herbs extract developed its immunomodulatory activity after inducement.
AB - Immunomodulator had a role in improving function and restoring the balance of the immune system. Research of immunomodulatory activity had been conducted and studied. Mimusops elengi leaves, Averrhoa carambola leaves and Curcuma xanthorrhiza rhizomes were mixed. The herbs were processed into a particle size. Various tests were performed to 5 groups of -white male rats. They were divided to the normal group (without treatment), positive control group induced with Imboost and 3 groups induced with various dose of herbs extract. The research showed mean total serum protein for regular group, the positive control group, dosage 1, 2, and 3 groups 8.56; 9.26; 9.71; 9.74 and 9.74g/dL, respectively. For a number of white pulp in the spleen, normal group, positive control, dosage 1, 2, and 3 groups resulted in 29, 27, 26, 27, and 20, respectively. These results indicated regulation with an inflammatory reaction. The mixed herbs extract developed its immunomodulatory activity after inducement.
KW - Averrhoa carambola
KW - Curcuma xanthorrhiza
KW - Histopathological Study
KW - Immunomodulatory Activity
KW - Mimusops elengi
UR - http://www.scopus.com/inward/record.url?scp=85064832074&partnerID=8YFLogxK
U2 - 10.1063/1.5096707
DO - 10.1063/1.5096707
M3 - Conference contribution
AN - SCOPUS:85064832074
T3 - AIP Conference Proceedings
BT - 3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
A2 - Wulan, Praswasti P.D.K.
A2 - Gozan, Misri
A2 - Astutiningsih, Sotya
A2 - Ramahdita, Ghiska
A2 - Dhelika, Radon
A2 - Kreshanti, Prasetyanugraheni
PB - American Institute of Physics Inc.
T2 - 3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
Y2 - 6 August 2018 through 8 August 2018
ER -