Determinant of postprandial triglyceride levels in healthy young adults

Tri J.E. Tarigan; Anandhara I. Khumaedi; Syahidatul Wafa; Michael Johan; Murdani Abdullah; Ingrid S. Surono; Dicky L. Tahapary

doi:10.1016/j.dsx.2019.04.027

Determinant of postprandial triglyceride levels in healthy young adults

Tri J.E. Tarigan, Anandhara I. Khumaedi, Syahidatul Wafa, Michael Johan, Murdani Abdullah, Ingrid S. Surono, Dicky L. Tahapary

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Background: Fasting lipid profile does not necessarily illustrate the exact lipid dynamic in 24 h as human spends most of their time in postprandial state. Postprandial triglyceride (TG)has been reported to have advantages compared to fasting TG in terms of practicality and ability to predict cardiovascular events. This study aims to assess the determinant of postprandial TG in healthy young adults. Methods: This is a quasy-experimental study that involved 200 healthy young adults. This study compared fasting with postprandial TG and analyzed the relationship between postprandial TG with various demographic and metabolic parameters after ingestion of standardized high fat liquid meal. Result: There was an upward trend from fasting TG to 2 h postprandial TG and 4 h postprandial TG. There was strong correlation between fasting TG and 2 h postprandial TG with 4 h postprandial TG (r = 0.731; p < 0.0001 dan r = 0.669; p < 0.0001, respectively). Whereas body mass index (BMI)and age showed weak correlation with 4 h postprandial TG (r = 0.141; p < 0.0001 dan r = 0.0747; p < 0.0001), fasting TG was the strongest predictor of 4 h postprandial TG (r = 0.669, B = 1.722 (95% CI 1.552 to 1.892), p < 0.0001). Conclusion: Fasting TG was the strongest determinant of 4 h postprandial TG in healthy young adults. We also observed strong correlation between 4 h postprandial TG and fasting TG. Hence, 4 h postprandial TG might potentially replaced fasting TG when measurement of fasting TG is not feasible.

Original language	English
Pages (from-to)	1917-1921
Number of pages	5
Journal	Diabetes and Metabolic Syndrome: Clinical Research and Reviews
Volume	13
Issue number	3
DOIs	https://doi.org/10.1016/j.dsx.2019.04.027
Publication status	Published - 1 May 2019

Keywords

Determinant
Fasting triglyceride
Postprandial triglyceride
Young adult

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.dsx.2019.04.027

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@article{788e203823014749a940c7b341e7e66d,

title = "Determinant of postprandial triglyceride levels in healthy young adults",

abstract = "Background: Fasting lipid profile does not necessarily illustrate the exact lipid dynamic in 24 h as human spends most of their time in postprandial state. Postprandial triglyceride (TG)has been reported to have advantages compared to fasting TG in terms of practicality and ability to predict cardiovascular events. This study aims to assess the determinant of postprandial TG in healthy young adults. Methods: This is a quasy-experimental study that involved 200 healthy young adults. This study compared fasting with postprandial TG and analyzed the relationship between postprandial TG with various demographic and metabolic parameters after ingestion of standardized high fat liquid meal. Result: There was an upward trend from fasting TG to 2 h postprandial TG and 4 h postprandial TG. There was strong correlation between fasting TG and 2 h postprandial TG with 4 h postprandial TG (r = 0.731; p < 0.0001 dan r = 0.669; p < 0.0001, respectively). Whereas body mass index (BMI)and age showed weak correlation with 4 h postprandial TG (r = 0.141; p < 0.0001 dan r = 0.0747; p < 0.0001), fasting TG was the strongest predictor of 4 h postprandial TG (r = 0.669, B = 1.722 (95% CI 1.552 to 1.892), p < 0.0001). Conclusion: Fasting TG was the strongest determinant of 4 h postprandial TG in healthy young adults. We also observed strong correlation between 4 h postprandial TG and fasting TG. Hence, 4 h postprandial TG might potentially replaced fasting TG when measurement of fasting TG is not feasible.",

keywords = "Determinant, Fasting triglyceride, Postprandial triglyceride, Young adult",

author = "Tarigan, {Tri J.E.} and Khumaedi, {Anandhara I.} and Syahidatul Wafa and Michael Johan and Murdani Abdullah and Surono, {Ingrid S.} and Tahapary, {Dicky L.}",

note = "Funding Information: The study was sponsored by Suntory Beverage and Food PTE LTD . The funder of the study had no role in study design, data collection, data interpretation, data analysis, or writing of the manuscript. Publisher Copyright: {\textcopyright} 2019 Diabetes India",

year = "2019",

month = may,

day = "1",

doi = "10.1016/j.dsx.2019.04.027",

language = "English",

volume = "13",

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journal = "Diabetes and Metabolic Syndrome: Clinical Research and Reviews",

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Determinant of postprandial triglyceride levels in healthy young adults. / Tarigan, Tri J.E.; Khumaedi, Anandhara I.; Wafa, Syahidatul; Johan, Michael; Abdullah, Murdani; Surono, Ingrid S.; Tahapary, Dicky L.

In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews, Vol. 13, No. 3, 01.05.2019, p. 1917-1921.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Determinant of postprandial triglyceride levels in healthy young adults

AU - Tarigan, Tri J.E.

AU - Khumaedi, Anandhara I.

AU - Wafa, Syahidatul

AU - Johan, Michael

AU - Abdullah, Murdani

AU - Surono, Ingrid S.

AU - Tahapary, Dicky L.

N1 - Funding Information: The study was sponsored by Suntory Beverage and Food PTE LTD . The funder of the study had no role in study design, data collection, data interpretation, data analysis, or writing of the manuscript. Publisher Copyright: © 2019 Diabetes India

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Background: Fasting lipid profile does not necessarily illustrate the exact lipid dynamic in 24 h as human spends most of their time in postprandial state. Postprandial triglyceride (TG)has been reported to have advantages compared to fasting TG in terms of practicality and ability to predict cardiovascular events. This study aims to assess the determinant of postprandial TG in healthy young adults. Methods: This is a quasy-experimental study that involved 200 healthy young adults. This study compared fasting with postprandial TG and analyzed the relationship between postprandial TG with various demographic and metabolic parameters after ingestion of standardized high fat liquid meal. Result: There was an upward trend from fasting TG to 2 h postprandial TG and 4 h postprandial TG. There was strong correlation between fasting TG and 2 h postprandial TG with 4 h postprandial TG (r = 0.731; p < 0.0001 dan r = 0.669; p < 0.0001, respectively). Whereas body mass index (BMI)and age showed weak correlation with 4 h postprandial TG (r = 0.141; p < 0.0001 dan r = 0.0747; p < 0.0001), fasting TG was the strongest predictor of 4 h postprandial TG (r = 0.669, B = 1.722 (95% CI 1.552 to 1.892), p < 0.0001). Conclusion: Fasting TG was the strongest determinant of 4 h postprandial TG in healthy young adults. We also observed strong correlation between 4 h postprandial TG and fasting TG. Hence, 4 h postprandial TG might potentially replaced fasting TG when measurement of fasting TG is not feasible.

AB - Background: Fasting lipid profile does not necessarily illustrate the exact lipid dynamic in 24 h as human spends most of their time in postprandial state. Postprandial triglyceride (TG)has been reported to have advantages compared to fasting TG in terms of practicality and ability to predict cardiovascular events. This study aims to assess the determinant of postprandial TG in healthy young adults. Methods: This is a quasy-experimental study that involved 200 healthy young adults. This study compared fasting with postprandial TG and analyzed the relationship between postprandial TG with various demographic and metabolic parameters after ingestion of standardized high fat liquid meal. Result: There was an upward trend from fasting TG to 2 h postprandial TG and 4 h postprandial TG. There was strong correlation between fasting TG and 2 h postprandial TG with 4 h postprandial TG (r = 0.731; p < 0.0001 dan r = 0.669; p < 0.0001, respectively). Whereas body mass index (BMI)and age showed weak correlation with 4 h postprandial TG (r = 0.141; p < 0.0001 dan r = 0.0747; p < 0.0001), fasting TG was the strongest predictor of 4 h postprandial TG (r = 0.669, B = 1.722 (95% CI 1.552 to 1.892), p < 0.0001). Conclusion: Fasting TG was the strongest determinant of 4 h postprandial TG in healthy young adults. We also observed strong correlation between 4 h postprandial TG and fasting TG. Hence, 4 h postprandial TG might potentially replaced fasting TG when measurement of fasting TG is not feasible.

KW - Determinant

KW - Fasting triglyceride

KW - Postprandial triglyceride

KW - Young adult

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U2 - 10.1016/j.dsx.2019.04.027

DO - 10.1016/j.dsx.2019.04.027

M3 - Article

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VL - 13

SP - 1917

EP - 1921

JO - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

JF - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

SN - 1871-4021

IS - 3

ER -

Determinant of postprandial triglyceride levels in healthy young adults

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Keywords

UN SDGs

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