Purpose: DPT-HB immunization is one of the mandatory basic immunizations given to children to prevent diphtheria, pertussis (whooping cough) and tetanus. Method: The study design was cross sectional. The sample in this study was based on secondary children record data of the 2018 IDHS consisting of DPT-HB/Pentavalent immunization; parental education; residential area; visits to health care facilities and ownership of health insurance. Results: The results of this study were obtained between parental education (p value: 0,0001, OR: 2,084) and the area of residence (p value: 0,028, OR: 0,637) having a relationship with DPT-HB / Pentavalent immunization. Conclusion: There is a significant relationship between the education of parents and the area of residence with DPT-HB immunization. Parental education has the strongest relationship with DPT-HB/Pentavalent immunization in children in West Java Province in 2017.