Design, synthesis and radical scavenging performance of 2,2'-(4,5-dihydro-1 H -pyrazol-3,5-dyl) diphenol

Bayu Ardiansah, Lina Mardiana, Ridla Bakri, N. P. Aziza, T. A. Baramanda

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Heterogeneous catalytic synthesis of a pyrazoline derivative, 2,2'-(4,5-dihydro-1H-pyrazol-3,5-dyl)diphenol from the reaction between (E)-1,3-bis(2-hydroxyphenyl)prop-2-en-1-one and hydrazine hydrate has been done using sodium impregnated on the activated chicken eggshells (Na-ACE). The agreement of the product structure was confirmed using FTIR, UV-Vis, and LC-ESI-MS instruments. This pyrazoline derivative has a significant activity to scavenge free radical of DPPH model in ethanol solution.

Original languageEnglish
Title of host publicationProceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017
EditorsRatna Yuniati, Terry Mart, Ivandini T. Anggraningrum, Djoko Triyono, Kiki A. Sugeng
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735417410
DOIs
Publication statusPublished - 22 Oct 2018
Event3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017 - Bali, Indonesia
Duration: 26 Jul 201727 Jul 2017

Publication series

NameAIP Conference Proceedings
Volume2023
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017
Country/TerritoryIndonesia
CityBali
Period26/07/1727/07/17

Keywords

  • activated chicken eggshells
  • antioxidant.
  • chalcone
  • heterogeneous catalyst
  • pyrazoline

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