TY - GEN
T1 - Design and development of pulse electromagnetic fields (PEMF) as adjuvant therapy for fracture healing
T2 - 3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
AU - Umiatin,
AU - Dilogo, Ismail Hadisoebroto
AU - Wijaya, Sastra Kusuma
AU - Sari, Puji
AU - Djaja, Andika Dwiputra
N1 - Publisher Copyright:
© 2019 Author(s).
PY - 2019/4/9
Y1 - 2019/4/9
N2 - This study aims to design and develop the pulsed electromagnetic fields (PEMF) device which can be utilized as an adjuvant therapy in delayed union fracture. In the first stage, Arduino-based PEMF device has been built with four main modules: pulse generator, user interface, Helmholtz coil and data acquisition system. Pulse generator allowing user to operate the physical parameters: frequency, duty cycle, burst duration and exposure duration. The Helmholtz coil could produce 1.6 mT of homogenous magnetic field. In the next stage, preliminary study was done to evaluate the effect of static magnetic field (SMF) and PEMF exposure on the healing of delayed union fracture model on Spraque Dawley (SD) rats. Six SD rats were fracturized at the femoral shaft by non-union model, then they were grouped into 2 groups, 1 (n = 3, SMFexposure, Bmax = 1.6 mT) and 2 (n = 3, PEMF exposure, Bmax = 1.6 mT frequency = 50Hz, duty cycle = 90%, burst cycle = 50%). Both groups had received the exposure for 4 hours per day and 7 hours per week. The evaluations of fracture healing were conducted by the histomorphometry analysis at 14, 21, and 28 days fracturization. PEMF group signal a better healing process through higher osseous tissue area.
AB - This study aims to design and develop the pulsed electromagnetic fields (PEMF) device which can be utilized as an adjuvant therapy in delayed union fracture. In the first stage, Arduino-based PEMF device has been built with four main modules: pulse generator, user interface, Helmholtz coil and data acquisition system. Pulse generator allowing user to operate the physical parameters: frequency, duty cycle, burst duration and exposure duration. The Helmholtz coil could produce 1.6 mT of homogenous magnetic field. In the next stage, preliminary study was done to evaluate the effect of static magnetic field (SMF) and PEMF exposure on the healing of delayed union fracture model on Spraque Dawley (SD) rats. Six SD rats were fracturized at the femoral shaft by non-union model, then they were grouped into 2 groups, 1 (n = 3, SMFexposure, Bmax = 1.6 mT) and 2 (n = 3, PEMF exposure, Bmax = 1.6 mT frequency = 50Hz, duty cycle = 90%, burst cycle = 50%). Both groups had received the exposure for 4 hours per day and 7 hours per week. The evaluations of fracture healing were conducted by the histomorphometry analysis at 14, 21, and 28 days fracturization. PEMF group signal a better healing process through higher osseous tissue area.
KW - delayed union
KW - fracture healing
KW - histomorphometry
KW - PEMF
UR - http://www.scopus.com/inward/record.url?scp=85064846934&partnerID=8YFLogxK
U2 - 10.1063/1.5096696
DO - 10.1063/1.5096696
M3 - Conference contribution
AN - SCOPUS:85064846934
T3 - AIP Conference Proceedings
BT - 3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
A2 - Wulan, Praswasti P.D.K.
A2 - Gozan, Misri
A2 - Astutiningsih, Sotya
A2 - Ramahdita, Ghiska
A2 - Dhelika, Radon
A2 - Kreshanti, Prasetyanugraheni
PB - American Institute of Physics Inc.
Y2 - 6 August 2018 through 8 August 2018
ER -