Description and Characteristic of Trihexyphenidyl Use in Patients Receiving Antipsychotic Therapy

Rudy Wijono, Martina W Nasrun, Charles E. Damping

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Extrapyramidal side effects (EPS) in the treatment of psychotic patients contribute to poor compliance and exacerbation of psychiatric symptoms. The use of trihexyphenidyl is beneficial in preventing and treating neuroleptic-induced EPS. The aim of this research is to find the pattern and characteristic of trihexyphenidyl usage in patients receiving antipsychotic therapy at Adult Psychiatry Clinic in Cipto Mangunkusumo Hospital.Method: This research is a descriptive cross sectional study. Samples used were medical records from patients who received trihexyphenidyl. Sample size of 97 subscrets was calculated from the formula for descriptive study. Samples were collected randomly from August 2010 to July 2011.Result: The most widely used pattern of trihexyphenidyl usage in patients receiving antipsychotic therapy was simultaneous use of trihexyphenidyl and antipsychotics since the beginning of treatment or prior to appearance of EPS at approximately 91.8%.Conclusion: This research has shown the pattern of trihexyphenidyl usage in PJD RSCM, which was to give trihexyphenidyl directly to patients without EPS examination and without evaluation every three months. This finding is not in accordance with the 2007 medical care guidelines from the Department of Psychiatry RSCM and WHO consensus on the management of EPS.
Original languageEnglish
JournalJournal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Publication statusPublished - 2013

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