TY - JOUR
T1 - Demographic Characteristics, Laboratory Findings, Radiological Features, and Outcomes of Patients with COVID-19: A Single-center Descriptive Study
AU - Rajabto, Wulyo
AU - Pramita, Prasna
AU - Tadjoedin, Hilman
AU - Gaol, Donnie Lumban
AU - Hardini, R.A. Sri
AU - Tarigan, Nirmala Purbasari
AU - Chandika, Vitya
AU - Manangka, Rumuat Semuel Wullul
AU - Pyrhadistya, Maria
PY - 2023/3/8
Y1 - 2023/3/8
N2 - The coronavirus disease 2019 (COVID-19) has resulted in a global crisis, affecting hundreds of millions of individuals, with Indonesia reporting a significant increase in cases in July 2021. Therefore, this study aims to describe the clinical, laboratory findings, radiological features, and outcomes of hospitalized patients with COVID-19. This retrospective study was carried out using 606 hospitalized COVID-19 patients who were admitted to the isolation ward in a Hospital in South Jakarta, Indonesia, from January 1 to April 30, 2021. The median age of the patients was 45 years, 55.6% were male, and 85.5% had non-severe diseases, with the most common presenting symptoms being fever, cough, and gastrointestinal symptoms. Patients with severe disease were significantly older (P<0.001), more likely to have hypertension (P<0.05) and diabetes (P<0.001), have an increased CRP (P<0.001), high ferritin (P<0.001), and increased d-dimer (P<0.001). Compared to patients who survived, patients who had died were older (P<0.001), had hypertension (P=0.013), increased CRP (P<0.001), high ferritin (P=0.002), and increased d-dimer (P=0.006). These results showed that older age, comorbidities, and a higher level of CRP, ferritin, and d-dimer increased the risk of severe disease and poor clinical outcomes in hospitalized COVID-19 patients.
AB - The coronavirus disease 2019 (COVID-19) has resulted in a global crisis, affecting hundreds of millions of individuals, with Indonesia reporting a significant increase in cases in July 2021. Therefore, this study aims to describe the clinical, laboratory findings, radiological features, and outcomes of hospitalized patients with COVID-19. This retrospective study was carried out using 606 hospitalized COVID-19 patients who were admitted to the isolation ward in a Hospital in South Jakarta, Indonesia, from January 1 to April 30, 2021. The median age of the patients was 45 years, 55.6% were male, and 85.5% had non-severe diseases, with the most common presenting symptoms being fever, cough, and gastrointestinal symptoms. Patients with severe disease were significantly older (P<0.001), more likely to have hypertension (P<0.05) and diabetes (P<0.001), have an increased CRP (P<0.001), high ferritin (P<0.001), and increased d-dimer (P<0.001). Compared to patients who survived, patients who had died were older (P<0.001), had hypertension (P=0.013), increased CRP (P<0.001), high ferritin (P=0.002), and increased d-dimer (P=0.006). These results showed that older age, comorbidities, and a higher level of CRP, ferritin, and d-dimer increased the risk of severe disease and poor clinical outcomes in hospitalized COVID-19 patients.
KW - COVID-19
KW - Coronavirus
KW - Demography
KW - Epidemiology
KW - Outcomes
UR - https://oamjms.eu/index.php/mjms/article/view/11554
U2 - 10.3889/oamjms.2023.11554
DO - 10.3889/oamjms.2023.11554
M3 - Article
SN - 1857-9655
VL - 11
SP - 163
EP - 168
JO - Open Access Macedonian Journal of Medical Sciences
JF - Open Access Macedonian Journal of Medical Sciences
IS - A
ER -