Cost-efficacy of skin grafting techniques using negative pressure wound therapy and tissue-engineered skin for burns

Muhammad Hanif Nadhif, Muhammad Satrio Utomo, Muhammad Farel Ferian, Farhan H. Taufikulhakim, Nadine H.P. Soerojo, Muhammad Dzulkarnaen Nain, Prasandhya A. Yusuf, Anindya P. Susanto, Theddeus O.H. Prasetyono

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Burns, which generate hypertrophic scar formation, may decrease functional and aesthetical aspects of patients' quality of life. To date, grafting treatments were not only proceeded solitarily. The technological development of burn treatments emerged with approaches, such as negative pressure wound therapy (NPWT) and tissue-engineered skin (TES). By incorporating negative pressure on the wound bed, NPWT was able to remove debris, remove exudates, maintain humidity, and improve epithelization. A latter development of wound management, TES, also showed prominent results of wound healing. Benefitting from tissue engineering approaches, TES provided the wound bed with extracellular matrix (ECM) and 3D structure to support wound healing. In some reports, NPWT was combined with TES to promote better efficacy. Unfortunately, the efficacies of NPWT, TES, or NPWT-TES hybrid as assisting approaches for skin drafting techniques are not reviewed yet, as well as the cost comparison of the three treatments. In this report, the comparison of skin grafting techniques assisted with the three treatments (NPWT, TES, or NPWT-TES hybrid) was investigated in terms of efficacy and cost. The review starts with brief technical aspects of the three treatments. Subsequently, the efficacy and cost analyses were discussed.

Original languageEnglish
Title of host publication5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020
EditorsKenny Lischer, Sugeng Supriadi, Siti Fauziyah Rahman, Yudan Whulanza
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735440869
DOIs
Publication statusPublished - 23 Mar 2021
Event5th International Symposium of Biomedical Engineering, ISBE 2020 - Depok, Virtual, Indonesia
Duration: 28 Jul 202029 Jul 2020

Publication series

NameAIP Conference Proceedings
Volume2344
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference5th International Symposium of Biomedical Engineering, ISBE 2020
CountryIndonesia
CityDepok, Virtual
Period28/07/2029/07/20

Keywords

  • cost
  • efficacy
  • grafting
  • NPWT
  • TES

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