TY - JOUR
T1 - Correlation of Patient Generated-subjective Global Assessment with Serum C-reactive Protein Level in Stage I–IV Head-and-neck Cancer
AU - Siregar, Anastasya
AU - Chandra, Dian Novita
AU - Rinaldi, Ikhwan
N1 - Funding Information:
The authors would like to thank Dr.dr. Diana Sunardi, M.Gizi, SpGK, Dr.dr. Ninik Mudjihartini, MS, Prof.Dr.dr. Saptawati Bardosono, MSc, dr. Syahrial M.Hutahuruk, Sp.THT-KL(K), and to the entire staff of the Department of Ear Nose Throat FMUI who had supported this study.
Publisher Copyright:
© 2022 Anastasya Siregar, Dian Novita Chandra, Ikhwan Rinaldi.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - AIM: This study aims to identify the correlation between patient generated-subjective global assessment (PG-SGA) with serum C-reactive protein (CRP) to be used to predict inflammation and prevent cachexia in head-and-neck cancer patients. METHODS: This was a cross-sectional study using 51 patients with inclusion criteria of patients diagnosed with head-and-neck cancer irrespective of stage, age ≥18 years old, had not received treatments of radiotherapy, chemotherapy, and surgery. The statistical analysis performed was Kolmogorov–Smirnov normality test, bivariate analysis by Spearman test, and linear regression analysis. RESULTS: As many as 64.7% of the patients had PG-SGA score ≥9 (average PG-SGA score 11.7 ± 6.2). The CRP median value was 6.4 (0.4–170.4) mg/L. There was a statistically significant positive but weak correlation between PG-SGA score with serum CRP (r = 0.372 and p = 0.007) and a significant linear relationship (r2 = 0.201). CONCLUSIONS: Malnutrition risk assessment using PG-SGA showed a high prevalence of malnutrition risk in head-and-neck cancer patients. PG-SGA score is correlated with serum CRP level. Further studies are needed to confirm the result of this study.
AB - AIM: This study aims to identify the correlation between patient generated-subjective global assessment (PG-SGA) with serum C-reactive protein (CRP) to be used to predict inflammation and prevent cachexia in head-and-neck cancer patients. METHODS: This was a cross-sectional study using 51 patients with inclusion criteria of patients diagnosed with head-and-neck cancer irrespective of stage, age ≥18 years old, had not received treatments of radiotherapy, chemotherapy, and surgery. The statistical analysis performed was Kolmogorov–Smirnov normality test, bivariate analysis by Spearman test, and linear regression analysis. RESULTS: As many as 64.7% of the patients had PG-SGA score ≥9 (average PG-SGA score 11.7 ± 6.2). The CRP median value was 6.4 (0.4–170.4) mg/L. There was a statistically significant positive but weak correlation between PG-SGA score with serum CRP (r = 0.372 and p = 0.007) and a significant linear relationship (r2 = 0.201). CONCLUSIONS: Malnutrition risk assessment using PG-SGA showed a high prevalence of malnutrition risk in head-and-neck cancer patients. PG-SGA score is correlated with serum CRP level. Further studies are needed to confirm the result of this study.
KW - C-reactive protein
KW - Head-and-neck cancer
KW - Malnutrition
KW - Patient generated-subjective global assessment
UR - http://www.scopus.com/inward/record.url?scp=85126033778&partnerID=8YFLogxK
U2 - 10.3889/oamjms.2022.8488
DO - 10.3889/oamjms.2022.8488
M3 - Article
AN - SCOPUS:85126033778
SN - 1857-5749
VL - 10
SP - 389
EP - 394
JO - Open Access Macedonian Journal of Medical Sciences
JF - Open Access Macedonian Journal of Medical Sciences
ER -
