Abstract
Background:Clinical Disease Activity Index (CDAI)
stands out amongst other methods in measuring disease
activity of rheumatoid arthritis (RA) patient. CDAI is
considered to be more practical and cost-effective
in daily practice because it requires no laboratory
examination. Previous studies conducted overseas
revealed that CDAI has good correlation compared to
other scoring index in measuring RA disease activity.
However, those studies only included pure RA patients
without any comorbidity diseases. Indonesian RA
patients have distinct clinical profile, in terms of
comorbidity conditions, and genetic predisposition which
affect the fenotype of the disease.
Objectives: Analyze correlation between CDAI
compared to Disease Activity Score 28 CRP (DAS28-
CRP) in measuring RA disease activity of RA patients in
Indonesia.
Methods: We conducted a cross sectional study to
RA patients who visited rheumatology clinic at Cipto
Mangunkusumo general hospital from April to May
2016. Data collected included history of illness, physical
examination, and recent laboratory results. All data were
documented in reseach's form. Both CDAI and DAS28-
CRP were measured in each patient by two observers.
Correlation analysis between two numeric datas from
CDAI and DAS28-CRP were measured with Spearman's
Rho. Overall performance was analyzed as additional
results using R2 index.
Result: A total of 119 subjects were included in this
study. All subjects were RA patients with comorbidities
and were representing quite numbers of Indonesian
races characteristic profile. Spearman's Rho = 0,918
and R2 index =0,831 (83,1%).
Conclusion: There is positive correlation result between
outcome of CDAI and outcome of DAS28-CRP in
assesing disease activity of Indonesian RA patients.
Original language | English |
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Pages (from-to) | 4-8 |
Journal | Indonesian Journal of Rheumatology |
Volume | 9 |
Issue number | 1 |
Publication status | Published - 1 Jan 2017 |
Keywords
- rheumatoid arthritis, Indonesia, correlation,Clinical Disease Activity Index