Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers

Em Yunir; Fajar Englando Alan Adesta; Aulia Rizka; Tri Juli Edi Tarigan

doi:10.12968/jowc.2021.0243

Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers

Em Yunir, Fajar Englando Alan Adesta, Aulia Rizka, Tri Juli Edi Tarigan

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment. Method: This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment. Results: The median value of 25(OH)D levels at initial treatment was 8ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86). Conclusion: The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.

Original language	English
Pages (from-to)	CLII-CLIX
Journal	Journal of wound care
Volume	33
DOIs	https://doi.org/10.12968/jowc.2021.0243
Publication status	Published - 1 Jun 2024

Keywords

25-hydroxyvitamin D
chronic wound
diabetic foot ulcer
granulation tissue
hard-to-heal
wound
wound care
wound dressing
wound healing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.12968/jowc.2021.0243

Cite this

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title = "Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers",

abstract = "Objective: To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment. Method: This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment. Results: The median value of 25(OH)D levels at initial treatment was 8ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86). Conclusion: The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.",

keywords = "25-hydroxyvitamin D, chronic wound, diabetic foot ulcer, granulation tissue, hard-to-heal, wound, wound care, wound dressing, wound healing",

author = "Em Yunir and Adesta, {Fajar Englando Alan} and Aulia Rizka and Tarigan, {Tri Juli Edi}",

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year = "2024",

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doi = "10.12968/jowc.2021.0243",

language = "English",

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TY - JOUR

T1 - Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers

AU - Yunir, Em

AU - Adesta, Fajar Englando Alan

AU - Rizka, Aulia

AU - Tarigan, Tri Juli Edi

PY - 2024/6/1

Y1 - 2024/6/1

N2 - Objective: To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment. Method: This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment. Results: The median value of 25(OH)D levels at initial treatment was 8ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86). Conclusion: The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.

AB - Objective: To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment. Method: This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment. Results: The median value of 25(OH)D levels at initial treatment was 8ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86). Conclusion: The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.

KW - 25-hydroxyvitamin D

KW - chronic wound

KW - diabetic foot ulcer

KW - granulation tissue

KW - hard-to-heal

KW - wound

KW - wound care

KW - wound dressing

KW - wound healing

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DO - 10.12968/jowc.2021.0243

M3 - Article

C2 - 38850545

AN - SCOPUS:85195533757

SN - 0969-0700

VL - 33

SP - CLII-CLIX

JO - Journal of wound care

JF - Journal of wound care

ER -

Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers

Abstract

Keywords

UN SDGs

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