Correction to: A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis (Clinical Pharmacokinetics, (2021), 10.1007/s40262-020-00971-2)

the Isoniazid Precision Dosing Group

Research output: Contribution to journalComment/debate

Abstract

The original text states that all volume and clearance parameters were allometrically scaled based on total body weight and that allometric scaling based on fat-free mass was not considered as height is not always readily available in TDM practice. During model development, we decided that height can easily be collected and allometric scaling based on fatfree mass should be considered. Allometric scaling based on fat-free mass was significantly better than scaling based on total body weight and was included in the final model. All volume and clearance parameters listed in Table 2 are applicable for a patient with a fat-free mass of 45 kg. This error affects the text in three places:

Original languageEnglish
Pages (from-to)955
Number of pages1
JournalClinical Pharmacokinetics
Volume60
Issue number7
DOIs
Publication statusAccepted/In press - 2021

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