TY - JOUR
T1 - Comprehensive evaluation on cancer of unknown primary site and how we managed it
T2 - A case report
AU - Yulian, Erwin Danil
AU - Hwei, Lie Rebecca Yen
AU - Tambun, Renaningtyas
AU - Siswoyo, Alvita Dewi
AU - Ham, Maria Fransisca
AU - Suroyo, Indrati
N1 - Funding Information:
The authors would like to thank Dr. Kevin Varian Marcevianto for assisting the publication of this study. None declared. No ethical approval was necessary. Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal on request. Not applicable. Not commissioned, externally peer-reviewed. Erwin Danil Yulian: Concept and design of case report, data collection, drafting, revision, approval of final manuscript. Lie Rebecca Yen Hwei: Concept and design of case report, revision, approval of final manuscript. Renaningtyas Tambun: Data collection, revision, approval of final manuscript. Alvita Dewi Siswoyo: Data collection, revision, approval of final manuscript. Maria Fransisca Ham: Data collection, revision, approval of final manuscript. Indrati Suroyo: drafting, revision, approval of final manuscript. Erwin Danil Yulian, M.D. Ph.D.
Publisher Copyright:
© 2022 The Authors
PY - 2022/4
Y1 - 2022/4
N2 - Introduction and importance: Cancer of unknown primary site (CUP) is metastatic cancer without primary tumor found from comprehensive medical history, physical examination, and regular laboratory examination. Eighty percent of CUP include unfavorable groups with 3 to 6 months of median survival despite chemotherapy treatment. Case presentation: A 52-year-old male was presented with a chief complaint of a recurrent lump in the neck and axilla. After comprehensive examinations over three years, the primary site of the metastatic tumor could not be found. Therefore, this patient was diagnosed with cancer of an unknown primary site. Clinical discussion: In patient with CUP, more precise therapy can only begin when the exact form of cancer is identified. However, the delay in diagnosis would worsen the patient's condition, as treatment measures cannot be implemented. Conclusion: Trimodal modalities including surgery, chemotherapy, and radiotherapy are suitable for CUP with squamous cell carcinoma proven in immunohistochemistry evaluation.
AB - Introduction and importance: Cancer of unknown primary site (CUP) is metastatic cancer without primary tumor found from comprehensive medical history, physical examination, and regular laboratory examination. Eighty percent of CUP include unfavorable groups with 3 to 6 months of median survival despite chemotherapy treatment. Case presentation: A 52-year-old male was presented with a chief complaint of a recurrent lump in the neck and axilla. After comprehensive examinations over three years, the primary site of the metastatic tumor could not be found. Therefore, this patient was diagnosed with cancer of an unknown primary site. Clinical discussion: In patient with CUP, more precise therapy can only begin when the exact form of cancer is identified. However, the delay in diagnosis would worsen the patient's condition, as treatment measures cannot be implemented. Conclusion: Trimodal modalities including surgery, chemotherapy, and radiotherapy are suitable for CUP with squamous cell carcinoma proven in immunohistochemistry evaluation.
KW - Axilla dissection
KW - Cancer of unknown primary site
KW - Metastatic cancer
KW - Radical neck dissection
KW - Squamous cell carcinoma
KW - Trimodal modalities
UR - http://www.scopus.com/inward/record.url?scp=85127007950&partnerID=8YFLogxK
U2 - 10.1016/j.ijscr.2022.106954
DO - 10.1016/j.ijscr.2022.106954
M3 - Article
AN - SCOPUS:85127007950
SN - 2210-2612
VL - 93
JO - International Journal of Surgery Case Reports
JF - International Journal of Surgery Case Reports
M1 - 106954
ER -
