Comparison tensile strength and histopathological evaluation of Wound healing process using adhesive skin tapes on laceration wounds of porcine skin

The procedures for closing a laceration wound vary. The efficacy of the new method using adhesive skin tape and its role in wound healing are unclear. Porcine skin is closely similar to human skin. This study was conducted on seven York Pork pigs in the laboratory of the Veterinary Teaching Hospital, Institut Pertanian, Bogor, Indonesia from August 2016 to September 2016. Three laceration wounds were made on the pig's back and closed using skin suture (group 1), the recommended application (group 2), and a modified application (group 3). Histopathological evaluation was performed on days 7 and 30 by biopsy; tensile strength was evaluated after 6 weeks' treatment. On day 7, there was a significant difference in the collagen deposition between groups 2 and 3, but there was no significant difference to group 1. There were no significant differences among the groups regarding subcutaneous fibroblasts and fibrocytes or tensile strength. The maximum force at rest was 380 ± 68.12 N. A modified application of adhesive skin tapes results in better collagen deposition and wound edge adaptation than the recommended application. However, the results of this method do not differ significantly from those of skin suture. Intradermal suture use increases tensile strength.