Comparison of auditory p300 in amphetamine users and non-users of other narcotics, psychotropics, and other addictive substances

Objectives: To measure latency period, amplitude of auditory P300 in amphetamine user and non-user of other narcotics, psychotropics and other addictive substances involving cognitive function. Material and methods: Descriptive research with crosssectional comparative study was used. Adult (18–40 years old) subjects, amphetamine, other narcotics, psychotropics and other addictive substances users and non-users were collected consecutively. Results: Fifteen subjects showed impaired cognitive function andwas significantly correlated shown by Fisher’s test. Median for latent period is longer in amphetamine users compared to non-users. Median amplitude in both groups are statistically insignificant. Conclusions: The median, both during the latency period and amplitude, for the two groups was still within the normal range. Nevertheless, there was a tendency for latency period to prolong amongst amphetamine users.