TY - JOUR
T1 - Comparative study of the two-period of epidemiological analysis of risk factors for breast cancer in indonesia. Does it change?
AU - Ramli, Muchlis
AU - Budiningsih, Setyawati
AU - Ohno, Yoshiyuki
AU - Tjindarbumi, Didid
AU - Sakamoto, Goi
AU - Cornain, Santoso
AU - Prihartono, Joedo
AU - Darwis, Idral
AU - Suzuki, Sadao
AU - Tjahjadi, Gunawan
AU - Wakai, Kenji
AU - Dillon, Drupadi S.
AU - Soetrisno, Esti
AU - Roostini, Endang Sri
AU - Watanabe, Susumu
N1 - Funding Information:
The authors are grateful to the nurses, Ms. Emi and Ms. Ros and for public health nurses, Ms. July and Ms. Erlaini for excellent care and collection of data of breast cancer cases and controls. We are also in-debted to the laboratory technician for excellent work on the surgico pathological specimens. This work was supported by the Ministry of Education, Science, Sports and Culture of Japanese Government, Grants No. 01042007, 04042013 and 06042006; and was partly supported by the Indonesian Cancer Foundation. This collaborative study was a part of Special Cancer Research Project in Mon-busho International Scientific Research Program, with the approval of the Dean, Faculty of Medicine University of Indonesia, No. 4383/PT02.H4.FK/E/88.
Funding Information:
This work was supported by the Ministry of Educa- tion, Science, Sports and Culture of Japanese Gov- ernment, Grants No. 01042007, 04042013 and O6042006; and was partly supported by the Indone- sian Cancer Foundation. This collaborative study was a part of Special Cancer Research Project in Mon- busho International Scientific Research Program, with the approval of the Dean, Faculty of Medicine University of Indonesia, No. 43831P'102.H4.FKÆ/
Publisher Copyright:
© 1999, Faculty of Medicine, Universitas Indonesia. All rights reserved.
PY - 1999/4/1
Y1 - 1999/4/1
N2 - A case control study of epidemiological aspect of breast cancer especially concerning the risk factors and lifestyles in breast cancer patients had been carried out twice in Indonesia. Firstly in 1980-1981 (one year), performed by the University of Indonesia, Faculty of Medicine, Department of Community Medicine and Department of Surgery and 90 cases of breast cancer were compared to 90 controls. In the second study, performed under the International Collaborative Study on Breast Cancer between Indonesia and Japan (University of Indonesia from Indonesia and Nagoya University and Cancer Institute Tokyo from Japan), 300 cases of breast cancer were compared to 600 matched controls. In comparative analysis between the two studies, the following findings were obtained, it was estimated that there was no change of age distribution of breast cancer, which peaked at the age group of 40-49. There was no significant change of the stage distribution of breast cancer, although early detection program pioneered by Indonesia Cancer Foundation had been carried out since twenty years ago. Ten years difference was seen between the first study and the second study, while the distribution of cases according to education did not change significantly. The result of risk factor analysis showed that only irradiation and history of trauma increased the risk of breast cancer significantly in the first study, while obese, marital status, illiterate, pregnancy and lactation did not cause significant difference. In the second study, it was found that marriage and irradiation had protective effect in the development of breast cancer; while separated, widowed status, illiterate, pregnancy, lactation and trauma were found as significant risk factors in breast cancer development.
AB - A case control study of epidemiological aspect of breast cancer especially concerning the risk factors and lifestyles in breast cancer patients had been carried out twice in Indonesia. Firstly in 1980-1981 (one year), performed by the University of Indonesia, Faculty of Medicine, Department of Community Medicine and Department of Surgery and 90 cases of breast cancer were compared to 90 controls. In the second study, performed under the International Collaborative Study on Breast Cancer between Indonesia and Japan (University of Indonesia from Indonesia and Nagoya University and Cancer Institute Tokyo from Japan), 300 cases of breast cancer were compared to 600 matched controls. In comparative analysis between the two studies, the following findings were obtained, it was estimated that there was no change of age distribution of breast cancer, which peaked at the age group of 40-49. There was no significant change of the stage distribution of breast cancer, although early detection program pioneered by Indonesia Cancer Foundation had been carried out since twenty years ago. Ten years difference was seen between the first study and the second study, while the distribution of cases according to education did not change significantly. The result of risk factor analysis showed that only irradiation and history of trauma increased the risk of breast cancer significantly in the first study, while obese, marital status, illiterate, pregnancy and lactation did not cause significant difference. In the second study, it was found that marriage and irradiation had protective effect in the development of breast cancer; while separated, widowed status, illiterate, pregnancy, lactation and trauma were found as significant risk factors in breast cancer development.
KW - Breast cancer
KW - Case-control study
KW - Epidemiological analysis
UR - http://www.scopus.com/inward/record.url?scp=85008640874&partnerID=8YFLogxK
U2 - 10.13181/mji.v8i2.693
DO - 10.13181/mji.v8i2.693
M3 - Article
AN - SCOPUS:85008640874
VL - 8
SP - 90
EP - 97
JO - Medical Journal of Indonesia
JF - Medical Journal of Indonesia
SN - 0853-1773
IS - 2
ER -